Results 171 to 180 of about 21,465 (238)

MolGramTreeNet: A multimodal molecular property prediction model via grammar tree-constrained molecular representation. [PDF]

iScience
Zhang Y, Liu W, Zhao H, Shao J, Pandiyan S, Yao M, Ni K, Wang L.   +7 more
europepmc   +1 more source

Palatable‐Food–Driven Top‐Down Circuit Inhibits PVNCRF Activity to Mitigate Stress Via Peri‐PVNCRFR1 Neurons

Advanced Science, EarlyView.
Palatable food alleviates stress and prevents anxiety. This study uncovers a dedicated neural pathway: dopamine release in the PFC activates D1R neurons, whose projections to the peri‐PVN engage a population of anxiolytic CRFR1 neurons. These neurons then inhibit stress‐induced hyperactivity of PVNCRF neurons, providing a circuit‐level explanation for ...
Yuchuan Hong, Shirui Jun, Tianjiao Deng, Gaojie Shao, Dan Liu, Yi Sun, Yan Chen, Qian Xiao, Jie Shao, Sheng Wang, Tianwen Huang, Fan Yang, Jie Tu   +12 more
wiley   +1 more source

FlowMol3: flow matching for 3D <i>de novo</i> small-molecule generation.

Digit Discov
Dunn I, Koes DR.
europepmc   +1 more source

GNN-MA: Soft Molecular Alignment with Cross-Graph Attention for Ligand-Based Virtual Screening. [PDF]

Molecules
Liu K, Wei D, Shi R, Zhou Z.
europepmc   +1 more source

Stage‐Specific H3K14 and H3K23 Succinylation Orchestrates Insect Metamorphosis and Oogenesis

Advanced Science, EarlyView.
Stage‐specific succinylation of histone H3 at lysine 14 and 23 differentially controls insect metamorphosis and oogenesis through distinct GPCR‐PKC signaling cascades, revealing an evolutionarily conserved epigenetic mechanism that coordinates key life‐history traits.
Yu‐Pu Jing, Lunjie Li, Libin Yang, Lin‐Jie Zhang, Qiang Yan, Ci Zhang, Zanrong Wen, Guangze Yu, Qian Li, Shutang Zhou   +9 more
wiley   +1 more source

Fuzzy logic based nonlinear blending hybrid control of a kestrel-inspired ornithopter operating in sinusoidal and dryden gusts. [PDF]

Sci Rep
Abbasi SH, Saudagar AKJ, Nouman A, Hennache ML.   +3 more
europepmc   +1 more source

Nano Carbon‐mesh with Excellent Bonding Performance via Hydro‐cage De‐shielding Strategy

Advanced Science, EarlyView.
A hydro‐cage de‐shielding strategy transforms cellulose‐based films into a dragonfly‐wing‐like nano carbon‐mesh (NCM) adhesive through instantaneous carbonization‐polymerization. The resulting NCM‐plywood achieves exceptional wet shear strength (1.24 MPa at 63°C), exceeding Class II plywood standards, and retains 0.73 MPa after boiling‐water cycles ...
Weijia Yang, Jianyong Wan, Hongda Guo, Haizhu Wu, Yongli Yang, Wenhe Bi, Zhengyong Yang, Chenghua Wang, Bertrand Charrier, Hisham Essawy, Antonio Pizzi, Xinyi Chen, Zhijun Chen, Guanben Du, Xiaojian Zhou   +14 more
wiley   +1 more source

Capsule graph networks for accurate and interpretable crystalline materials property prediction. [PDF]

J Cheminform
Sure EK, Wu X, Qian Q.
europepmc   +1 more source

PIEZO1 is Required for Acute Myeloid Leukemia Progression and Leukemia Stem Cell Maintenance via HIF1A‐SLC7A11 Axis‐Mediated Ferroptosis Defense

Advanced Science, EarlyView.
This study identifies the mechanosensor PIEZO1 as a key factor in promoting acute myeloid leukemia progression and uncovers a ferroptosis defense system mediated by PIEZO1‐HIF1A‐SLC7A11 axis that is essential for leukemia stem cell maintenance. This ferroptotic defense system may represent a unique vulnerability for leukemia stem cells, providing a ...
Tiantian Zhang, Ziyan Cao, Kexin Gao, Shuxin Yao, Yanbing Zheng, Manman Cui, Rong Yin, Guoqiang Han, Jin Hu, Chengyi Wang, Haojian Zhang   +10 more
wiley   +1 more source

GlycanGT: a pretrained graph transformer framework for glycan graph representation and generative learning. [PDF]

Bioinformatics
Kitani A, Zhang B, Himori K, Matsui Y.
europepmc   +1 more source