Results 131 to 140 of about 217,155 (332)

Spin-structures and 2-fold coverings

open access: yesBoletim da Sociedade Paranaense de Matemática, 2005
We prove that the existence of a Spin-structure on an oriented realvector bundle and the number of them can be obtained in terms of 2-fold coverings of the total space of the SO(n)-principal bundle associated to the vector bundle. Basically we use theory
Maria Hermínia de Paula Leite Mello   +2 more
doaj  

Co‐overexpression of the caloric restriction‐induced mitochondrial factors PGC‐1α and MIPEP upregulates Phospho1 expression in adipocytes

open access: yesFEBS Open Bio, EarlyView.
Caloric restriction that extends lifespan induces the expression of PGC‐1α and MIPEP in white adipose tissue. In this study, co‐overexpression of Pgc‐1α and Mipep upregulated the gene expression of PHOSPHO1. These findings provide new insights into mitochondria‐related mechanisms underlying the effects of caloric restriction in adipocytes.
Mamiko Ishimatsu   +9 more
wiley   +1 more source

On projectivized vector bundles and positive holomorphic sectional curvature

open access: yes, 2016
We generalize a construction of Hitchin to prove that, given any compact K\"ahler manifold $M$ with positive holomorphic sectional curvature and any holomorphic vector bundle $E$ over $M$, the projectivized vector bundle ${\mathbb P}(E)$ admits a K ...
Alvarez, Angelynn   +2 more
core  

The E3 ubiquitin ligase, RNF219, suppresses CNOT6L expression to exhibit antiproliferative activity

open access: yesFEBS Open Bio, EarlyView.
We identified RNF219 as a CCR4‐NOT complex‐interacting E3 ubiquitin ligase that targets the CCR4‐NOT subunit CNOT6L for ubiquitination. RNF219 directly binds to the DUF3819 domain of CNOT1 through its putative α‐helix spanning amino acids 521–542. Our findings also suggest that antiproliferative activity of RNF219 is at least partially mediated by ...
Shou Soeda   +9 more
wiley   +1 more source

The Lie Algebra of Smooth Sections of a T-bundle

open access: yesInternational Journal of Industrial Engineering and Production Research, 2006
In this article, we generalize the concept of the Lie algebra of vector fields to the set of smooth sections of a T-bundle which is by definition a canonical generalization of the concept of a tangent bundle.
M. Nadjafikhah, H. R. Salimi Moghaddam
doaj  

Whole‐Blood RNA Sequencing Profiling of Patients With Rheumatoid Arthritis Treated With Tofacitinib

open access: yesACR Open Rheumatology, EarlyView.
Objective Patients with rheumatoid arthritis (RA) often fail to respond to therapies, including JAK inhibitors (JAKi), and treatment allocation is made via a trial‐and‐error strategy. A comprehensive analysis of responses to JAKi, including tofacitinib, by RNA sequencing (RNAseq) would allow the discovery of transcriptomic markers with a two‐fold ...
Chiara Bellocchi   +11 more
wiley   +1 more source

A geometry for Lagrangians on the bundle R^n x T^1_n M [PDF]

open access: yesRendiconti di Matematica e delle Sue Applicazioni, 1998
This article is concerned with some geometric structures of the jetbundle IR^n ×T ^1_nM, modelled by the non autonomous tangent bundle geometry. We use this fact to construct similar objects like a particular family of vector fields and we study its ...
P.R. Rodrigues
doaj  

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