Results 91 to 100 of about 2,245,201 (365)

Population genomics of the Asian tiger mosquito, Aedes albopictus. Insights into the recent worldwide invasion [PDF]

, 2017
Aedes albopictus, the “Asian tiger mosquito,” is an aggressive biting mosquito native to Asia that has colonized all continents except Antarctica during the last ~30–40 years. The species is of great public health
Aguirre-Obando, Alexander, Armbruster, Baird, Becker, Beebe, Benedict, Birungi, Bonizzoni, Brady, Brown, Chen, Chen, Chouin-Carneiro, Dalla Pozza, Damal, Danecek, Das, Delatte, Denlinger, Eaton, Egizi, Emerson, Excoffier, Flacio, Foll, Frichot, Galtier, Gloria-Soria, Goubert, Gratz, Hawley, Hemingway, Hurst, Ismail, Jackson, Jombart, Kambhampati, Kambhampati, Kamgang, Kamgang, Kasai, Lamballerie, Lambrechts, Langmead, Lewis, Li, Lischer, Liu, Lounibos, Lounibos, Lourenco de Oliveira, Luu, Manni, Manni, Marcombe, Maynard, Medley, Medlock, Minard, Morens, Mori, Mousson, Nazareno, O'Donnell, Patterson, Paupy, Pech-May, Peterson, Porretta, Porretta, Powell, Puckett, Reiter, Smartt, Sprenger, Stamatakis, Tatem, Trucchi, Urbanelli, Urbanski, Willing, Wong, Wray, Wu, Xu, Zhong   +86 more
core   +2 more sources

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source

Structural and functional characterization of chitinase from carnivorous plant Drosera adelae

FEBS Open Bio, EarlyView.
A class I chitinase from the carnivorous plant Drosera adelae was expressed and purified using a yeast system, revealing high enzymatic activity. Structural analyses of the catalytic and chitin‐binding domains identified key tyrosine residues involved in substrate binding, offering insights into the enzyme's adaptation for insect digestion.
Kazunari Yoneda, Yuki Naruse, Yusaku Suizu, Tomohiro Araki, Yoshikazu Hoshi, Haruhiko Sakuraba, Junji Hayashi, Toshihisa Ohshima   +7 more
wiley   +1 more source

Transovarial Transmission of Anaplasma marginale in Rhipicephalus (Boophilus) microplus Ticks Results in a Bottleneck for Strain Diversity

Pathogens, 2023
Anaplasma marginale is an obligate intraerythrocytic bacterium of bovines, responsible for large economic losses worldwide. It is mainly transmitted by Rhipicephalus (Boophilus) microplus ticks and, despite mounting evidence suggesting transovarial ...
Sofía de la Fournière, Eliana Carolina Guillemi, Martina Soledad Paoletta, Agustina Pérez, Dasiel Obregón, Alejandro Cabezas-Cruz, Néstor Fabián Sarmiento, Marisa Diana Farber   +7 more
doaj   +1 more source

Positioning for conceptual development using latent semantic analysis [PDF]

, 2009
With increasing opportunities to learn online, the problem of positioning learners in an educational network of content offers new possibilities for the utilisation of geometry-based natural language processing techniques.
Burek, Gaston, Hoisl, Bernhard, Wild, Fridolin   +2 more
core   +1 more source

Do mosquitoes transmit the avian malaria-like parasite Haemoproteus? An experimental test of vector competence using mosquito saliva [PDF]

, 2016
[Background] The life-cycle of many vector-borne pathogens includes an asexual replication phase in the vertebrate host and sexual reproduction in the insect vector. However, as only a small array of parasites can successfully develop infective phases
Figuerola, Jordi, Gangoso, Laura, Gutiérrez-López, Rafael, Martínez de la Puente, Josué, Soriguer, Ramón C., Yan, Jiayue   +5 more
core   +1 more source

Differential vector competence of Ornithodoros soft ticks for African swine fever virus: What if it involves more than just crossing organic barriers in ticks?

Parasites & Vectors, 2020
Several species of soft ticks in genus Ornithodoros are known vectors and reservoirs of African swine fever virus (ASFV). However, the underlying mechanisms of vector competence for ASFV across Ornithodoros species remain to be fully understood.
Rémi Pereira de Oliveira, E. Hutet, R. Lancelot, F. Paboeuf, Maxime Duhayon, F. Boinas, A. A. Pérez de León, S. Filatov, M. Le Potier, L. Vial   +9 more
semanticscholar   +1 more source

Structural and functional analysis of Bacillus sarcosine oxidase and its activity toward cyclic imino acids

FEBS Open Bio, EarlyView.
Sarcosine oxidase from Bacillus sp. (SoxB) recognizes l‐proline (l‐Pro), d‐proline (d‐Pro), and l‐thioproline (l‐Tpr) as minor substrates. In this study, we measured their absorption spectra, determined the crystal structures of their enzyme complexes, and performed site‐directed mutagenesis of key residues.
Yuqi Zhang, Yoshitaka Nakajima, Masae Kurobe, Tsutomu Nakamura, Tomoki Himiyama, Yoshiaki Nishiya   +5 more
wiley   +1 more source

Vector Competence of Aedes aegypti, Aedes albopictus and Culex quinquefasciatus from Brazil and New Caledonia for Three Zika Virus Lineages

Pathogens, 2020
Zika virus (ZIKV) has caused severe epidemics in South America beginning in 2015, following its spread through the Pacific. We comparatively assessed the vector competence of ten populations of Aedes aegypti and Ae.
R. S. Fernandes, O. O'Connor, M. I. Bersot, D. Girault, Marguerite R Dokunengo, N. Pocquet, M. Dupont-Rouzeyrol, R. Lourenço-de-Oliveira   +7 more
semanticscholar   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source