Results 101 to 110 of about 2,190,858 (340)

Structural Porosity and Low Mineral Density in Enamel Rods Drive Molar Incisor Hypomineralisation

open access: yesAdvanced Functional Materials, EarlyView.
This study uses advanced imaging modalities on multiple length scales to show that molar‐incisor hypomineralization does not present as a locally homogeneous pathology. Instead, microstructural defects, characterized through non‐mineralized, protein‐rich sheaths and an altered mineral structure in between prism rods, resulting in local differences in ...
Katharina Jähn‐Rickert   +14 more
wiley   +1 more source

N-linked glycosylation of the West Nile virus envelope protein is not a requisite for avian virulence or vector competence.

open access: yesPLoS Neglected Tropical Diseases, 2019
The N-linked glycosylation motif at amino acid position 154-156 of the envelope (E) protein of West Nile virus (WNV) is linked to enhanced murine neuroinvasiveness, avian pathogenicity and vector competence.
Payal D Maharaj   +11 more
doaj   +1 more source

Exploring Lutzomyia longipalpis sand flies vector competence to Leishmania major parasites.

open access: yesJournal of Infectious Diseases, 2020
Lutzomyia longipalpis sand flies are the major natural vector of Leishmania infantum parasites, responsible for the transmission of visceral leishmaniasis in the New World.
P. Cecílio   +6 more
semanticscholar   +1 more source

Poly(lactic‐co‐glycolic acid) Nanoparticles for IL‐12 Self‐Amplifying RNA Delivery in Glioblastoma Models

open access: yesAdvanced Functional Materials, EarlyView.
xxxx. ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain cancers, with median survival rarely exceeding 15 months after diagnosis. Interleukin‐12 (IL‐12) is a potent immunostimulatory cytokine capable of reshaping the tumor microenvironment (TME), yet its clinical translation is hindered by systemic toxicity and short half‐life. RNA‐based
Fatima Hameedat   +11 more
wiley   +1 more source

Temporal Dynamics of ‘Ca. Phytoplasma mali’ Load in the Insect Vector Cacopsylla melanoneura

open access: yesInsects, 2020
The transmission of phytoplasmas is the result of an intricate interplay involving pathogens, insect vectors and host plants. Knowledge of the vector’s competence during its lifespan allows us to define more sustainable well-timed control strategies ...
Valentina Candian   +2 more
doaj   +1 more source

Color Routing and Beam Steering of Single‐Molecule Emission with a Spherical Silicon Nanoantenna

open access: yesAdvanced Functional Materials, EarlyView.
We experimentally demonstrate broadband directional emission from single molecules using a single spherical silicon nanoparticle assembled via DNA origami. By varying nanoparticle (NP) size and emitter position, we achieve unidirectional emission, beam steering, and color routing at the nanoscale, revealing modal interference as the underlying ...
María Sanz‐Paz   +9 more
wiley   +1 more source

Effect of Serotype and Strain Diversity on Dengue Virus Replication in Australian Mosquito Vectors

open access: yesPathogens, 2020
Dengue virus (DENV) is the most important mosquito-borne viral pathogen of humans, comprising four serotypes (DENV-1 to -4) with a myriad of genotypes and strains.
O’mezie Ekwudu   +6 more
doaj   +1 more source

Mosquitoes as Arbovirus Vectors: From Species Identification to Vector Competence

open access: yes, 2018
Mosquitoes and other arthropods transmit a large number of medically important pathogens, in particular viruses. These arthropod-borne viruses (arboviruses) include a wide variety of RNA viruses belonging to the Flaviviridae family (West Nile virus (WNV), Usutu virus (USUV), Dengue virus (DENV), Japanese encephalitis virus (JEV), Zika virus (ZIKV ...
Schulz, Claudia   +1 more
openaire   +1 more source

Microphysiological Systems of Lymphatics and Immune Organs

open access: yesAdvanced Healthcare Materials, EarlyView.
This review surveys recent progress in engineering lymphatic microenvironments and immune organoids within microphysiological systems, emphasizing innovative strategies to recreate the biochemical and biophysical complexity of native lymphatic tissues.
Ishita Jain   +2 more
wiley   +1 more source

Vector Competence for Dengue-2 Viruses Isolated from Patients with Different Disease Severity [PDF]

open access: gold, 2020
Ronald Enrique Morales Vargas   +3 more
openalex   +1 more source

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