Results 141 to 150 of about 2,245,201 (365)

Silicon‐Integrated Next‐Generation Plasmonic Devices for Energy‐Efficient Semiconductor Applications

Advanced Materials Technologies, EarlyView.
Silicon (Si)‐integrated plasmonics offer a pathway to next‐generation, energy‐efficient semiconductor applications. This review highlights advances using complementary metal–oxide–semiconductor (CMOS)‐compatible materials like transparent conductive oxides and novel architectures, particularly coupled hybrid plasmonic waveguides (CHPWs).
Nasir Alfaraj, Amr S. Helmy
wiley   +1 more source

Mosquito vector competence for dengue is modulated by insect-specific viruses

Nature Microbiology, 2023
R. P. Olmo, Yaovi M. H. Todjro, E. Aguiar, J. P. P. de Almeida, F. Ferreira, Juliana N. Armache, Isaque J. S. de Faria, Álvaro G A Ferreira, Siad C. G. Amadou, A. T. S. Silva, Kátia P. R. de Souza, A. P. Vilela, Antinéa Babarit, C. Tan, M. Diallo, A. Gaye, C. Paupy, Judicaël Obame-Nkoghe, Tessa M. Visser, C. Koenraadt, M. Wongsokarijo, A. L. C. Cruz, M. T. Prieto, M. C. Parra, M. Nogueira, V. Avelino-silva, Renato N. Mota, M. Borges, B. Drumond, E. Kroon, M. Recker, L. Sedda, E. Marois, J. Imler, J. Marques   +34 more
semanticscholar   +1 more source

Integrin α8‐Mediated Pericyte Morphogenesis Controls Blood‐Brain Barrier Integrity

Advanced Science, EarlyView.
This study highlights that ITGA8 impacts pericyte morphology and function, both crucial for BBB integrity, via RhoA/ROCK signaling, thus influencing TGF‐β1 activation through cytoskeletal tension and ECM interactions. Notably, in post‐ischemic recovery models, ITGA8 deficiency exacerbates vascular dysfunction by impairing pericyte‐mediated BBB ...
Chang‐Xiong Gong, Lin‐Lin Hu, Ling Jiang, Pei‐Xia Shi, Shuang Zhang, Yuan Zhao, Bing‐Qiao Wang, Xiao‐Feng Cheng, Cheng‐Kang He, Sen Lin, Yue Dai, Zhao‐You Meng, Chen‐Hao Zhao, Bao‐Liang Sun, Qi Xie, Fang‐Fei Li, Qing‐Wu Yang   +16 more
wiley   +1 more source

A review of filarial nematodes parasitizing tick vectors: unraveling global patterns in species diversity, host associations, and interactions with tick-borne pathogens

Parasites & Vectors
Ticks are well-known vectors of pathogens, including filarial nematodes, which can affect animal and human health. This review synthesizes current knowledge of filarial nematodes that utilize ticks as vectors, focusing on the Onchocercidae.
Oluwaseun D. Ajileye, Guilherme G. Verocai, Jessica E. Light   +2 more
doaj   +1 more source

Mayaro virus, a potential threat for Europe: vector competence of autochthonous vector species. [PDF]

Parasit Vectors
Abstract Background Mayaro virus (MAYV) is an emerging alphavirus, primarily transmitted by the mosquito Haemagogus janthinomys in Central and South America. However, recent studies have shown that Aedesaegypti, Aedesalbopictus and various Anopheles mosquitoes can also transmit the virus under laboratory conditions. MAYV
Brustolin M, Bartholomeeusen K, Rezende T, Ariën KK, Müller R.   +4 more
europepmc   +4 more sources

HERV‐K TM Subunit Elicits CD8+ T Cell Anergy and Tumor Immune Evasion via Targeting CD3 Coreceptor ε in AML and PDAC

Advanced Science, EarlyView.
Novel viral immune checkpoint K‐TM subunit is aberrantly expressed in CD8+ T cells and enriched in sera of cancer patients, inducing CD8+ T cell anergy and eliciting potent tumor immune escape in mouse model. Mechanistically, K‐TM directly targets and induces the phosphorylation of CD3ε receptor.
Mengyuan Li, Shuwen Zheng, Qinyuan Gong, Zhaoxing Wu, Wen Lei, Wanyue Cao, Ping Wang, Xuzhao Zhang, Wenbin Qian, Yun Liang, Ying Lu, Fenglin Li, Qi Zhang, Rongzhen Xu   +13 more
wiley   +1 more source

Human iPSC‐Derived Mononuclear Phagocytes Improve Cognition and Neural Health across Multiple Mouse Models of Aging and Alzheimer's Disease

Advanced Science, EarlyView.
Short‐term intravenous treatments with iPSC‐derived mononuclear phagocytes (iMPs) improve cognitive decline and neural health in two mouse models of aging and in the 5xFAD mouse model of Alzheimer's disease. iMPs reduce levels of serum amyloid proteins that increase in aging and improve the health of hippocampal microglia and mossy cells.
V. Alexandra Moser, Luz Jovita Dimas‐Harms, Rachel M. Lipman, Jake Inzalaco, Shaughn Bell, Michelle Alcantara, Erikha Valenzuela, George Lawless, Simion Kreimer, Sarah J. Parker, Helen S. Goodridge, Clive N. Svendsen   +11 more
wiley   +1 more source

The GGH/HuR Complex Binds and Stabilizes mRNAs to Maintain Tumor Cell Cycle and DNA Replication

Advanced Science, EarlyView.
Despite its canonical role in inhibiting DNA synthesis, GGH promotes tumor growth as a novel RNA‐binding protein. GGH binds GC‐rich 5′UTRs (e.g., CDC6/CCND1), recruits HuR to form a ternary complex that stabilizes mRNA via circular conformation, fueling DNA replication and the cell cycle. Targeting this axis suppresses NSCLC progression.
Yu Li, Xinrui Li, Yuhui Du, Sijie Chen, Xiaoniu He, Zhangrong Xie, Zhiqing Zhou, Huijie Zhao, Xiaofei Zeng, Guoan Chen   +9 more
wiley   +1 more source

Investigations of Koutango Virus Infectivity and Dissemination Dynamics in Aedes aegypti Mosquitoes

Environmental Health Insights, 2014
Aedes aegypti has already been implicated in the emergence of dengue and chikungunya viruses in the southern US. Vector competence is the ability of a mosquito species to support transmission of an arbovirus, which is bounded by its ability to support ...
Jaime M. de Araújo Lobo, Rebecca C. Christofferson, Christopher N. Mores   +2 more
doaj   +1 more source

Vector competence of Aedes aegypti, Aedes albopictus, and Culex quinquefasciatus mosquitoes for Mayaro virus

bioRxiv, 2019
Newly emerging or re-emerging arthropod-borne viruses (arboviruses) are important causes of human morbidity and mortality nearly worldwide. Arboviruses such as Dengue (DENV), Zika (ZIKV), Chikungunya (CHIKV) and West Nile virus (WNV) underwent an ...
T. N. Pereira, F. D. Carvalho, Silvana de Mendonça, M. Rocha, L. Moreira   +4 more
semanticscholar   +1 more source