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Generation of Replication-Competent and -Defective HSV Vectors

Cold Spring Harbor Protocols, 2011
INTRODUCTIONEngineering effective vectors has been crucial to the efficient delivery and expression of therapeutic gene products in vivo. Among these, HSV-1 represents an excellent candidate vector for delivery to the peripheral and central nervous systems. The natural biology of HSV-1 includes the establishment of a lifelong latent state in neurons in
William F, Goins   +5 more
openaire   +2 more sources

Vector Competence Assays for RVFV in Mosquitoes

Rift Valley fever virus (RVFV) is the causative agent of Rift Valley fever, a mosquito-borne zoonotic febrile illness that primarily affects ruminants, camels, and humans. It is endemic in sub-Saharan Africa and the Arabian Peninsula, albeit with the potential to spread to and establish in non-endemic countries where mosquito vectors are present ...
Lotty, Birnberg, Núria, Busquets
openaire   +2 more sources

Effect of Vector Density and Competence on Macromolecular Vector Transformation Efficiency

2016
To research the effects of vector quantity and competence on the positive cloning rate, with a known gene sequence but in the absence of DNA template, we artificially designed 26 primers to synthesize a target gene of 835 bp in vitro using overlapping PCR technique.
QIN, Hongni   +3 more
openaire   +1 more source

Influences of the Mosquito Microbiota on Vector Competence

2016
Abstract Mosquitoes have a diverse intestinal microbiota which plays essential roles in a variety of the insect's physiological functions. This microbiota can also influence vector competence for human pathogens in multiple ways, including immune system activation or suppression, the regulation of other physiological processes, direct inhibition of ...
S. van Tol, G. Dimopoulos
openaire   +1 more source

Assessing the Impact of Insecticide Resistance on Vector Competence: A Review

Insects, 2022
Victoria Pando-Robles   +2 more
exaly  

Vector Competence

2008
John B. Heppner   +19 more
openaire   +1 more source

Vector competence

2001
Scott C. Weaver   +4 more
openaire   +1 more source

Genetics of Insect Vector Competence for Arboviruses

1994
Ever since arthropods were first incriminated as vectors of disease, medical and veterinary entomologists have recognized that identification of the particular arthropod species transmitting a disease agent is critical for understanding disease epidemiology and for effective disease control.
openaire   +1 more source

Vector Competence for DENV-2 Among Aedes albopictus (Diptera: Culicidae) Populations in China

Frontiers in Cellular and Infection Microbiology, 2021
Jiatian Wang   +2 more
exaly  

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