Results 231 to 240 of about 147,779 (282)

Lack of Vector Competence in UK Culex pipiens molestus for Oropouche Virus

Pilgrim J, Sy VE, Multeau Q, Komarasamy TV, Kohl A, Blagrove MS, Tanianis-Hughes J, Medlock J, Sanders C, Baylis M, Dietrich I.   +10 more
europepmc   +1 more source

Vector Competence of Aedes aegypti from São Tomé and Príncipe for West Nile Virus Transmission. [PDF]

Microorganisms
Marmé R, Tomaz F, Sousa CA, Pinto J, Lanzaro GC, Parreira R, Seixas G.   +6 more
europepmc   +1 more source

RBD‐SD1 Nanoparticle Vaccines From DPP4‐Using Merbecoviruses Elicit a Cross‐Reactive Antibody Response but Limited Cross‐Protective Immunity

Biotechnology and Bioengineering, EarlyView.
SpyCatcher‐mi3 nanoparticles displaying RBD‐SD1 from MERS‐CoV, NL140422, and HKU4 elicited robust and cross‐reactive IgG responses in mice. Only MERS‐CoV RBD‐SD1 induced neutralizing antibodies against MERS‐CoV and protected human DPP4 mice from a MERS‐CoV challenge, indicating conserved serologic but limited cross‐neutralizing epitopes.
Peter J. Halfmann, Jeong Soo Lee, Tong Wang, Augustine Duffy, Janie E. Rogers, Natasha Chen, Elizabeth Frimpong, Carmen Rai, Yoshihiro Kawaoka, Ravi S. Kane   +9 more
wiley   +1 more source

Review of dengue vectors in Cambodia: distribution, bionomics, vector competence, control and insecticide resistance. [PDF]

Parasit Vectors
Doeurk B, Marcombe S, Maquart PO, Boyer S.   +3 more
europepmc   +1 more source

Engineering Murine Cross‐Reactivity Into an Affibody to Human Death Receptor 5

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Interspecies cross‐reactive protein therapeutics that target conserved epitopes across species are critical for translational research. The present study showcases the engineering of an affibody molecule, originally discovered for binding to human death receptor 5 (hDR5) with 94 nM affinity, to simultaneously acquire cross‐reactivity to murine
Tse‐Han Kuo, Nagamani Vunnam, Jonathan N. Sachs, Benjamin J. Hackel   +3 more
wiley   +1 more source

Evaluating vector competence for Yellow fever in the Caribbean. [PDF]

Nat Commun
Gabiane G, Bohers C, Mousson L, Obadia T, Dinglasan RR, Vazeille M, Dauga C, Viglietta M, Yébakima A, Vega-Rúa A, Gutiérrez Bugallo G, Gélvez Ramírez RM, Sonor F, Etienne M, Duclovel-Pame N, Blateau A, Smith-Ravin J, De Lamballerie X, Failloux AB.   +18 more
europepmc   +1 more source

Engineered B7‐H3 Binding in Modular Gp2 Miniproteins

Biotechnology and Bioengineering, EarlyView.
ABSTRACT B7‐H3, an important immune checkpoint modulator of T‐cell function, is a tumor vasculature biomarker and is overexpressed in a variety of cancers. Its expression is associated with tumor growth, metastasis, and poor clinical prognosis, which makes B7‐H3 an appealing target for diagnostics and therapeutics.
Abbigael Harthorn, Hannah K. Windsor, Zachary Schmitz, Nathaniel Cheung, Ebube Agwaramgbo, Benjamin J. Hackel   +5 more
wiley   +1 more source

<i>Oropouche orthobunyavirus</i> in Urban Mosquitoes: Vector Competence, Coinfection, and Immune System Activation in <i>Aedes aegypti</i>. [PDF]

Viruses
de Mendonça SF, Baldon LVR, Todjro YMH, Marçal BA, Rodrigues MEC, Moreira RL, Santos EC, Rocha MN, de Faria IJDS, Silva BDM, Pereira TN, de Freitas AC, Duarte MM, Iani FCM, Guimarães NR, Adelino TER, Giovanetti M, Alcantara LCJ, Ferreira ÁGA, Moreira LA.   +19 more
europepmc   +1 more source

Overcoming intranasal delivery barriers with ultrastable polyzwitterionic siRNA nanocages for enhanced glioblastoma therapy

BMEMat, EarlyView.
A ROS‐responsive, zwitterionic nanocage enables stable, intranasal siRNA delivery to glioblastoma, promoting deep tumor penetration via non‐degradative pathways and trigeminal nerve transport. This platform achieves durable gene silencing and tumor suppression, offering a non‐invasive, storage‐stable strategy for treating glioma and other neurological ...
Jingwen Xie, Jingxing Si, Xiaobei Deng, Jing Tan, Ruijie Zhu, Jizhou Qi, Gaoxia Ma, Bin Wang, Yi Wang, Yunzhou Guo, Yuping Chen, Shiqun Shao, Youqing Shen   +12 more
wiley   +1 more source

Vector competence of Culex quinquefasciatus for Tembusu virus and viral factors for virus transmission by mosquitoes. [PDF]

Vet Res
Tang Y, He Y, Wang X, Wu Z, Du S, Wang M, Jia R, Zhu D, Liu M, Zhao X, Yang Q, Wu Y, Zhang S, Huang J, Ou X, Sun D, Cheng A, Chen S.   +17 more
europepmc   +1 more source