Results 251 to 260 of about 147,779 (282)

Mosquito Immunobiology: The Intersection of Vector Health and Vector Competence

Annual Review of Entomology, 2018
As holometabolous insects that occupy distinct aquatic and terrestrial environments in larval and adult stages and utilize hematophagy for nutrient acquisition, mosquitoes are subjected to a wide variety of symbiotic interactions. Indeed, mosquitoes play host to endosymbiotic, entomopathogenic, and mosquito-borne organisms, including protozoa, viruses,
Lyric C, Bartholomay, Kristin, Michel
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Rearing temperature influences flavivirus vector competence of mosquitoes

Medical and Veterinary Entomology, 1989
ABSTRACT. Culex annulirostris Skuse mosquitoes (Brisbane strain) were reared at 20 o C or 27°C and the adult females were experimentally infected by feeding Murray Valley encephalitis virus (MVE).
B H, Kay, I D, Fanning, P, Mottram
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Replication-competent retrovirus vectors for cancer gene therapy

Frontiers in Bioscience, 2008
Oncolytic virotherapy represents an emerging field with tremendous promise for harnessing the replicative capabilities of viruses against rapidly proliferating cancer cells. Among the different replicating virus technologies being tested, replication-competent retrovirus (RCR) vectors based on murine leukemia virus (MLV) exhibit unique characteristics.
Chien-Kuo, Tai, Noriyuki, Kasahara
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Modification of arthropod vector competence via symbiotic bacteria

Parasitology Today, 1993
Some of the world's most devastating diseases are transmitted by arthropod vectors. Attempts to control these arthropods are currently being challenged by the widespread appearance of insecticide resistance. It is therefore desirable to develop alternative strategies to complement existing methods of vector control. In this review, Charles Beard, Scott
Beard, C. B., O'Neill, S. L., Tesh, R. B., Richards, F. F., Aksoy, S.   +4 more
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Vector Competence of Australian Mosquitoes for Chikungunya Virus

Vector-Borne and Zoonotic Diseases, 2010
Chikungunya virus (CHIKV) is a globally emerging arbovirus responsible for unprecedented outbreaks in the western Indian Ocean, the Indian subcontinent and Italy. To assess the receptivity of Australia to CHIKV, we exposed 10 Australian mosquito species to a 2006 strain of CHIKV isolated from a viremic traveler from Mauritius. In susceptibility trials,
Van Den Hurk, AF, Hall-Mendelin, S, Pyke, AT, Smith, GA, Mackenzie, JS   +4 more
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Generation of Replication-Competent and -Defective HSV Vectors

Cold Spring Harbor Protocols, 2011
INTRODUCTIONEngineering effective vectors has been crucial to the efficient delivery and expression of therapeutic gene products in vivo. Among these, HSV-1 represents an excellent candidate vector for delivery to the peripheral and central nervous systems. The natural biology of HSV-1 includes the establishment of a lifelong latent state in neurons in
William F, Goins, David M, Krisky, James B, Wechuck, Darren, Wolfe, Shaohua, Huang, Joseph C, Glorioso   +5 more
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Antibody-Mediated Targeting of Replication-Competent Retroviral Vectors

Human Gene Therapy, 2003
Replication-competent murine leukemia virus (MLV) vectors can be engineered to achieve high efficiency gene transfer to solid tumors in vivo and tumor-restricted replication, however their safety can be further enhanced by redirecting tropism of the virus envelope. We have therefore tested the targeting capability and replicative stability of ecotropic
Chien-Kuo, Tai, Christopher R, Logg, Jinha M, Park, W French, Anderson, Michael F, Press, Noriyuki, Kasahara   +5 more
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Monitoring Lentivirus Vector Stocks for Replication-Competent Viruses

Cold Spring Harbor Protocols, 2018
The potential emergence of replication-competent lentiviruses (RCLs) during vector production and the significant biosafety risk that this represents has led to the development of lentivirus vector production systems to minimize the risk of generating RCLs.
Miguel, Sena-Esteves, Guangping, Gao
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Vector Competence Assays for RVFV in Mosquitoes

Rift Valley fever virus (RVFV) is the causative agent of Rift Valley fever, a mosquito-borne zoonotic febrile illness that primarily affects ruminants, camels, and humans. It is endemic in sub-Saharan Africa and the Arabian Peninsula, albeit with the potential to spread to and establish in non-endemic countries where mosquito vectors are present ...
Lotty, Birnberg, Núria, Busquets
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Effect of Vector Density and Competence on Macromolecular Vector Transformation Efficiency

2016
To research the effects of vector quantity and competence on the positive cloning rate, with a known gene sequence but in the absence of DNA template, we artificially designed 26 primers to synthesize a target gene of 835 bp in vitro using overlapping PCR technique.
QIN, Hongni, ZHANG, Lanlan, QIN, Hongni, ZHANG, Lanlan   +3 more
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