Results 21 to 30 of about 1,296,944 (267)

Age and sex distribution trends of SARS-CoV-2 infections: Insights from three epidemic waves in Puducherry, India

Journal of Infection in Developing Countries
Introduction: This study analyzed the age and sex distribution of COVID-19 patients during the initial three COVID-19 waves in Puducherry, India, from August 2020 to March 2022, to understand the distribution of infection across different demographic ...
Lourduraj John De Britto, Arya Rahul, Dinesh Sundaram, Balakrishnan Vijayakumar, Thirumal Sankari, Muthukumaravel Subramanian, Raja Jeyapal Dinesh, Philip Raj Abraham, Panneer Devaraju, Yasin Nazeer, Ayyanar Elango, Balasubramaniyan Ramalingam, Kulandaisamy Athisaya Mary, Suchi Tyagi, Rituraj Niranjan, Paramasivan Rajaiah, Mayilsamy Muniaraj, Narendran Pradeep Kumar, Irudayaraj Geetha, Ananganallur Nagarajan Shriram, Adinarayanan Srividya, Vijesh Sreedhar Kuttiatt, Ashwani Kumar   +22 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Microbiome diversity in mosquitoes and sand flies: implications for vector competence

Parasites & Vectors
Mosquitoes and sand flies are the most important vectors of several human diseases. A comprehensive analysis of the diversity and composition of the microbiome in mosquitoes and sandflies is important.
Gnanasekar Ragini, Mahima K. Mani, Rohit Sharma, Nikhil Bharadwaj, Muthukumaravel Subramanian, Shriram Ananganallur Nagarajan, Manju Rahi   +6 more
doaj   +1 more source

An evolutionary game study of cockroach control strategies in residential households

Scientific Reports, 2023
Cockroach control in Beijing's residential households is supported by the local government previously but now it is paid by the residents themselves. Under the new residential household cockroach control strategy, the evolutionary game theory is applied ...
Qiuhong Li, Meide Liu, Ting Liu, Ying Tong, Yong Zhang   +4 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Evaluation of the mosquitocidal efficacy of fluralaner, a potential candidate for drug based vector control

Scientific Reports
Vector control is a key intervention against mosquito borne diseases. However, conventional methods have several limitations and alternate strategies are in urgent need. Vector control with endectocides such as ivermectin is emerging as a novel strategy.
Harish Kumar Shah, Vaishnavi Srinivasan, Shakila Venkatesan, Vijayakumar Balakrishnan, Sadanandane Candasamy, Nisha Mathew, Ashwani Kumar, Vijesh Sreedhar Kuttiatt   +7 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Seasonal dynamics and species diversity of Anopheles mosquitoes in malaria endemic districts of Southern Odisha India

Scientific Reports
Mosquitoes of the Anopheles, Aedes, and Culex genera are responsible for transmitting major vector-borne diseases. Malaria remains a significant public health concern in Odisha, primarily due to the state’s conducive environment for Anopheles mosquito ...
Muhammed Mustafa Baig, Divya Teja Koppula, Dilip Kumar Panigrahi, B. Vijayakumar, Dolly Choudhary, Premalatha Acharya, Manoj Patnaik, K. Gunasekaran, Ashwani Kumar, Manju Rahi, A. N. Shriram   +10 more
doaj   +1 more source

Insecticide-treated eave nets and window screens for malaria control in Chalinze district, Tanzania: a study protocol for a household randomised control trial

Trials, 2022
Background Long-lasting insecticidal nets (LLINs) have contributed to the reduction of malaria in sub-Saharan Africa, including Tanzania. However, they rely on daily user behaviour and high coverage which is difficult to maintain.
Olukayode G. Odufuwa, Sarah Jane Moore, Zawadi Mageni Mboma, Emmanuel Mbuba, Joseph Barnabas Muganga, Jason Moore, Rose Philipo, Mohammed Ally Rashid, Rune Bosselmann, Ole Skovmand, John Bradley   +10 more
doaj   +1 more source

Studies on the fitness characteristics of wMel- and wAlbB-introgressed Aedes aegypti (Pud) lines in comparison with wMel- and wAlbB-transinfected Aedes aegypti (Aus) and wild-type Aedes aegypti (Pud) lines

Frontiers in Microbiology, 2022
Wolbachia, an intracellular maternally transmitted endosymbiont, has been shown to interfere with the replication of dengue virus in Aedes aegypti mosquitoes. The Wolbachia-transinfected Ae.
Candasamy Sadanandane, Kasinathan Gunasekaran, Devaraju Panneer, Sarala K. Subbarao, Manju Rahi, Balakrishnan Vijayakumar, Velan Athithan, Annamalai Sakthivel, Sundaram Dinesh, Purushothaman Jambulingam   +9 more
doaj   +1 more source