Results 41 to 50 of about 3,256,056 (300)

Evaluation of the mosquitocidal efficacy of fluralaner, a potential candidate for drug based vector control

Scientific Reports
Vector control is a key intervention against mosquito borne diseases. However, conventional methods have several limitations and alternate strategies are in urgent need. Vector control with endectocides such as ivermectin is emerging as a novel strategy.
Harish Kumar Shah, Vaishnavi Srinivasan, Shakila Venkatesan, Vijayakumar Balakrishnan, Sadanandane Candasamy, Nisha Mathew, Ashwani Kumar, Vijesh Sreedhar Kuttiatt   +7 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Seasonal dynamics and species diversity of Anopheles mosquitoes in malaria endemic districts of Southern Odisha India

Scientific Reports
Mosquitoes of the Anopheles, Aedes, and Culex genera are responsible for transmitting major vector-borne diseases. Malaria remains a significant public health concern in Odisha, primarily due to the state’s conducive environment for Anopheles mosquito ...
Muhammed Mustafa Baig, Divya Teja Koppula, Dilip Kumar Panigrahi, B. Vijayakumar, Dolly Choudhary, Premalatha Acharya, Manoj Patnaik, K. Gunasekaran, Ashwani Kumar, Manju Rahi, A. N. Shriram   +10 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

An improved two-vector model predictive torque control based on RMS duty ratio optimization for pmsm [PDF]

This paper proposes an improved two-vector model-predictive torque control (MPTC) strategy to reduce the average torque ripple and improve the flux tracking performance.
De Belie, Frederik, Li, Huayu, Ma, Chenwei, Yao, Xuliang   +3 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Detection of Wuchereria bancrofti infection in mosquitoes in areas co-endemic with Brugia malayi in Balasore district, Odisha, India

Scientific Reports
Lymphatic filariasis (LF) is a crippling and disfiguring parasitic condition. India accounts for 55% of the world’s LF burden. The filarial parasite Wuchereria bancrofti is known to cause 99.4% of the cases while, Brugia malayi accounts for 0.6% of the ...
Philip Raj Abraham, Balasubramaniyan Ramalingam, Priyadarshini Mohapatra, Kaliannagounder Krishnamoorthy, Sugeerappa Laxmanappa Hoti, Ashwani Kumar   +5 more
doaj   +1 more source

The Centres for Disease Control light trap (CDC-LT) and the human decoy trap (HDT) compared to the human landing catch (HLC) for measuring Anopheles biting in rural Tanzania

Malaria Journal, 2022
Background Vector mosquito biting intensity is an important measure to understand malaria transmission. Human landing catch (HLC) is an effective but labour-intensive, expensive, and potentially hazardous entomological surveillance tool.
Isaac Haggai Namango, Carly Marshall, Adam Saddler, Amanda Ross, David Kaftan, Frank Tenywa, Noely Makungwa, Olukayode G. Odufuwa, Godfrey Ligema, Hassan Ngonyani, Isaya Matanila, Jameel Bharmal, Jason Moore, Sarah J. Moore, Manuel W. Hetzel   +14 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Mating of unfed, engorged, and partially to fully gravid Aedes aegypti (Diptera: Culicidae) female mosquitoes in producing viable eggs

Parasites & Vectors
Background Understanding the relationship between blood-feeding and mating is important in effectively managing the most well-adapted vector insect, Aedes aegypti (Linnaeus).
Muniaraj Mayilsamy, Surendiran Subramani, Rajamannar Veeramanoharan, Asifa Vijayakumar, Amuthalingam T. Asaithambi, Arthi Murugesan, Nandhakumar Selvaraj, Vijayakumar Balakrishnan, Paramasivan Rajaiah   +8 more
doaj   +1 more source