Results 51 to 60 of about 11,411,963 (305)

Made-to-Measure Malaria Vector Control Strategies: Rational Design Based on Insecticide Properties and Coverage of Blood Resources for Mosquitoes. [PDF]

, 2014
Eliminating malaria from highly endemic settings will require unprecedented levels of vector control. To suppress mosquito populations, vector control products targeting their blood hosts must attain high biological coverage of all available sources ...
Drakeley, Christopher J., Chitnis, Nakul, Gerry F Killeen, Nakul Chitnis, Aklilu Seyoum, Stevenson, Jennifer C, Jennifer C Stevenson, Seyoum, Aklilu, Killeen, Gerry F., Killeen, Gerry, Drakeley, Christopher J, John E Gimnig, Killeen, Gerry F, Christopher J Drakeley, Gimnig, John E, Stevenson, Jennifer C., Gimnig, John E.   +16 more
core   +1 more source

Evaluation of the mosquitocidal efficacy of fluralaner, a potential candidate for drug based vector control

Scientific Reports
Vector control is a key intervention against mosquito borne diseases. However, conventional methods have several limitations and alternate strategies are in urgent need. Vector control with endectocides such as ivermectin is emerging as a novel strategy.
Harish Kumar Shah, Vaishnavi Srinivasan, Shakila Venkatesan, Vijayakumar Balakrishnan, Sadanandane Candasamy, Nisha Mathew, Ashwani Kumar, Vijesh Sreedhar Kuttiatt   +7 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Insecticide resistance in Culex quinquefasciatus from Zanzibar: implications for vector control programmes. [PDF]

, 2012
\ud \ud Zanzibar has a long history of lymphatic filariasis (LF) caused by the filarial parasite Wuchereria bancrofti, and transmitted by the mosquito Culex quinquefasciatus Say.
Ali, Abdullah S., Mohammed, Khalfan, Khalfan Mohammed, Khatib, Bakari O., Machin, Camille, Kelly-Hope Louise A, Louise A Kelly-Hope, Ali, Abdullah S, Jones, Chris, Mcha Juma, Mohammed Khalfan, Khatib, Bakari O, Juma Mcha, Ranson, Hilary, McHa, Juma, Jones Christopher M, Abdullah S Ali, Kelly-Hope, Louise, Ranson, Hilary; id_orcid, Silas Majambere, Majambere Silas, Christopher M Jones, Bakari O Khatib, Kelly-Hope, Louise A, Machin Camille, Ali Abdullah S, Camille Machin, Jones, Christopher M, Khatib Bakari O, Majambere, Silas, Hilary Ranson, Ranson Hilary   +31 more
core   +1 more source

Seasonal dynamics and species diversity of Anopheles mosquitoes in malaria endemic districts of Southern Odisha India

Scientific Reports
Mosquitoes of the Anopheles, Aedes, and Culex genera are responsible for transmitting major vector-borne diseases. Malaria remains a significant public health concern in Odisha, primarily due to the state’s conducive environment for Anopheles mosquito ...
Muhammed Mustafa Baig, Divya Teja Koppula, Dilip Kumar Panigrahi, B. Vijayakumar, Dolly Choudhary, Premalatha Acharya, Manoj Patnaik, K. Gunasekaran, Ashwani Kumar, Manju Rahi, A. N. Shriram   +10 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Malaria transmission after five years of vector control on Bioko Island, Equatorial Guinea. [PDF]

, 2012
BACKGROUND: Malaria is endemic with year-round transmission on Bioko Island. The Bioko Island Malaria Control Project (BIMCP) started in 2004 with the aim to reduce malaria transmission and to ultimately eliminate malaria.
Matias, Abrahan, Abaga Simon, Segura Luis, Slotman Michel A, Kleinschmidt, Immo, Reddy Michael R, Simon Abaga, Vamsi P Reddy, Reddy Vamsi P, Kulkarni, Vani, Abrahan Matias, Abaga, Simon, Kleinschmidt, I., Christopher Schwabe, Kulkarni, V., Overgaard Hans J, Slotman, Michel A, Reddy, V. P., Kleinschmidt Immo, Slotman, M. A., Overgaard, H. J., Reddy, M. R., Vani Kulkarni, Hans J Overgaard, Michael R Reddy, Matias Abrahan, Schwabe Christopher, Michel A Slotman, Schwabe, C., Reddy, Vamsi P, Kulkarni Vani, Immo Kleinschmidt, Luis Segura, Segura, L., Segura, Luis, Matias, A., Schwabe, Christopher, Abaga, S., Reddy, Michael R, Overgaard, Hans J   +39 more
core   +1 more source

Insecticide-treated eave nets and window screens for malaria control in Chalinze district, Tanzania: a study protocol for a household randomised control trial

Trials, 2022
Background Long-lasting insecticidal nets (LLINs) have contributed to the reduction of malaria in sub-Saharan Africa, including Tanzania. However, they rely on daily user behaviour and high coverage which is difficult to maintain.
Olukayode G. Odufuwa, Sarah Jane Moore, Zawadi Mageni Mboma, Emmanuel Mbuba, Joseph Barnabas Muganga, Jason Moore, Rose Philipo, Mohammed Ally Rashid, Rune Bosselmann, Ole Skovmand, John Bradley   +10 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Detection of Wuchereria bancrofti infection in mosquitoes in areas co-endemic with Brugia malayi in Balasore district, Odisha, India

Scientific Reports
Lymphatic filariasis (LF) is a crippling and disfiguring parasitic condition. India accounts for 55% of the world’s LF burden. The filarial parasite Wuchereria bancrofti is known to cause 99.4% of the cases while, Brugia malayi accounts for 0.6% of the ...
Philip Raj Abraham, Balasubramaniyan Ramalingam, Priyadarshini Mohapatra, Kaliannagounder Krishnamoorthy, Sugeerappa Laxmanappa Hoti, Ashwani Kumar   +5 more
doaj   +1 more source