Results 51 to 60 of about 1,296,944 (267)

Evaluation of polyclonal antibodies raised in rabbits against dengue NS1 antigen

Scientific Reports
Dengue, a vector-borne disease caused by the dengue virus (DENV), is spread by Aedes mosquitoes like, Aedes aegypti and Aedes albopictus. In the absence of antiviral drugs or vaccines, dengue prevention is centered on mosquito vector control.
Philip Raj Abraham, Panneer Devaraju, Bharath L, Eiriene Prasad, Vidhya shree S, Akash Dhotre, Naveen Kumar Ramachandrappa, Surekha Mullapudi Venkata, Ashwani Kumar   +8 more
doaj   +1 more source

“In starvation, a bone can also be meat”: a mixed methods evaluation of factors associated with discarding of long-lasting insecticidal nets in Bagamoyo, Tanzania

Malaria Journal, 2022
Background Between 2000 and 2019, more than 1.8 billion long-lasting insecticidal nets (LLINs) were distributed in Africa. While the insecticidal durability of LLINs is around 3 years, nets are commonly discarded 2 years post distribution.
Edith P. Madumla, Sarah J. Moore, Jason Moore, Emmanuel Mbuba, Edgar M. Mbeyela, Ummi A. Kibondo, Selemani C, Mmbaga, Dickson Kobe, Jitihada Baraka, Daniel Msellemu, Johnson K. Swai, Zawadi M. Mboma, Olukayode G. Odufuwa   +13 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Acute undifferentiated febrile illness in a traveler returning from Burkina Faso, West Africa to Puducherry, India- a case report

BMC Infectious Diseases
Background Imported malaria remains a significant diagnostic challenge, particularly in regions approaching elimination. This case report is novel in its exploration of the complexities involved in diagnosing malaria imported from a high-endemic area to ...
Srikanth Srirama, Krishan Kumar Sihag, Anand Kumar Chandrasekaran, Neethi Prasannan Latha, Waseema Arif, Balaji Sampath Kumar, Panneer Devaraju   +6 more
doaj   +1 more source

Insights into animal reservoir hosts for the circulation of Leishmania parasite in the sustainable phase of National Kala-azar Elimination Programme in India

One Health
Background: India, currently in the sustained phase of visceral leishmaniasis elimination, continues to face challenges due to reports of indigenous cases from emerging foci, detection of parasitic DNA in multiple sand fly species, and the potential ...
Prasanta Saini, H.A. Haritha, B. Sivalaxmi, Harish Kumar Shah, P.A. Fathima, S. Amritha Naick, T. Kiruthiga, P.M. Ajithlal, R.S. Aiswarya, R. Paramasivan, M. Muniyaraj, Bidyut Nandi, S. Nandakumar, Manju Rahi   +13 more
doaj   +1 more source

The Biological Control of the Malaria Vector [PDF]

Toxins, 2012
The call for malaria control, over the last century, marked a new epoch in the history of this disease. Many control strategies targeting either the Plasmodium parasite or the Anopheles vector were shown to be effective. Yet, the emergence of drug resistant parasites and insecticide resistant mosquito strains, along with numerous health, environmental,
openaire   +3 more sources

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

FEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile, Riccardo Diamanti, Daniel Lundin, Soni Sharma, Robin Lissner, Coenraad P. Kuil, Martin Högbom, Dirk Bald, Dan Sjöstrand   +8 more
wiley   +1 more source

Ticks (Argasidae and Ixodidae) in Tehran Province, Central Iran: Distribution and Seasonal Activity

Veterinary Medicine International
Ticks are obligatory ectoparasites of vertebrates and can transmit pathogens, including: arboviruses, bacteria, and parasites to humans and animals worldwide.
Mojtaba Beik-Mohammadi, Maryam Tavassoli, Zakkyeh Telmadarraiy, Hassan Vatandoost, Farrokh Dabiri   +4 more
doaj   +1 more source