Results 61 to 70 of about 11,911,509 (308)

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Mating of unfed, engorged, and partially to fully gravid Aedes aegypti (Diptera: Culicidae) female mosquitoes in producing viable eggs

Parasites & Vectors
Background Understanding the relationship between blood-feeding and mating is important in effectively managing the most well-adapted vector insect, Aedes aegypti (Linnaeus).
Muniaraj Mayilsamy, Surendiran Subramani, Rajamannar Veeramanoharan, Asifa Vijayakumar, Amuthalingam T. Asaithambi, Arthi Murugesan, Nandhakumar Selvaraj, Vijayakumar Balakrishnan, Paramasivan Rajaiah   +8 more
doaj   +1 more source

Comparison of the human-baited double net trap with the human landing catch for Aedes albopictus monitoring in Shanghai, China

Parasites & Vectors, 2018
Background Human landing catch (HLC) is the most efficient method for Aedes monitoring, but it is not ethical due to its high risk of human exposure to pathogens. We designed trials to assess the performance of an alternative human-baited double net trap
Qiang Gao, Fei Wang, Xihong Lv, Hui Cao, Jianjun Zhou, Fei Su, Chenglong Xiong, Peien Leng   +7 more
doaj   +1 more source

A set of ontologies to drive tools for the control of vector-borne diseases [PDF]

, 2009
We are developing a set of ontologies that deal with vector-borne diseases and the arthropod vectors that transmit them. For practical reasons (application priorities), we initiated this project with an ontology of insecticide resistance followed by a ...
Christos Louis, Pantelis Topalis, Inga Siden-Kiamos, Emmanuel Dialynas, Elvira Mitraka, Elena Deliyanni   +5 more
core   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Spatial targeted vector control is able to reduce malaria prevalence in the highlands of Burundi. [PDF]

, 2008
In a highland province of Burundi, indoor residual spraying and long-lasting insecticidal net distribution were targeted in the valley, aiming also to protect the population living on the hilltops.
Baza, D., Van Herp, M, Maes, P., Baza, D, Baza, Dismas, d' Alessandro, Umberto, Protopopoff, Natacha, Van Bortel, W., Maes, Peter, D'Alessandro, U., Protopopoff, N., Van Herp, Michel, Coosemans, Marc, D'Alessandro, Umberto, Van Herp, M., Coosemans, M, Maes, P, Coosemans, M., Van Bortel, W, D'Alessandro, U, Van Bortel, Wim, Marcotty, T, Marcotty, Tanguy, Marcotty, T., Protopopoff, N   +24 more
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Made-to-measure malaria vector control strategies : rational design based on insecticide properties and coverage of blood resources for mosquitoes [PDF]

, 2014
Eliminating malaria from highly endemic settings will require unprecedented levels of vector control. To suppress mosquito populations, vector control products targeting their blood hosts must attain high biological coverage of all available sources ...
Drakeley, Christopher J., Chitnis, Nakul, Gerry F Killeen, Nakul Chitnis, Aklilu Seyoum, Stevenson, Jennifer C, Jennifer C Stevenson, Seyoum, Aklilu, Killeen, Gerry F., Killeen, Gerry, Drakeley, Christopher J, John E Gimnig, Killeen, Gerry F, Christopher J Drakeley, Gimnig, John E, Stevenson, Jennifer C., Gimnig, John E.   +16 more
core   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source