Results 61 to 70 of about 3,234,434 (300)

Spatial justice and health (in)equity: the case of vector-borne diseases

open access: yesHumanities & Social Sciences Communications
From a spatial justice perspective, this article argues that the spatial plane is ‘constructed’ and that socio-spatial configurations can create and intensify health inequities for vulnerable sections. Employing a mixed methods design, the study inquired
Anoop C. Choolayil   +6 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Innovative sterile male release strategies for Aedes mosquito control: progress and challenges in integrating evidence of mosquito population suppression with epidemiological impact

open access: yesInfectious Diseases of Poverty
Background Aedes mosquitoes pose a significant global threat as vectors for several debilitating arboviruses, including dengue, Zika, yellow fever, and chikungunya.
Arya Rahul   +4 more
doaj   +1 more source

Transcriptomics and disease vector control [PDF]

open access: yesBMC Biology, 2010
Next-generation sequencing can be used to compare transcriptomes under different conditions. A study in BMC Genomics applies this approach to investigating the effects of exposure to a range of xenobiotics on changes in gene expression in the larvae of Aedes aegypti, the mosquito vector of dengue fever.
Ranson Hilary, Vontas John, Alphey Luke
openaire   +4 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Spin vector control of a spinning space station [PDF]

open access: yes, 1971
Digital computer program simulates system and related functions. Program is intended for, but not limited to, altitude control studies of rotating space station.
Hendricks, T.
core   +1 more source

Evaluation of polyclonal antibodies raised in rabbits against dengue NS1 antigen

open access: yesScientific Reports
Dengue, a vector-borne disease caused by the dengue virus (DENV), is spread by Aedes mosquitoes like, Aedes aegypti and Aedes albopictus. In the absence of antiviral drugs or vaccines, dengue prevention is centered on mosquito vector control.
Philip Raj Abraham   +8 more
doaj   +1 more source

“In starvation, a bone can also be meat”: a mixed methods evaluation of factors associated with discarding of long-lasting insecticidal nets in Bagamoyo, Tanzania

open access: yesMalaria Journal, 2022
Background Between 2000 and 2019, more than 1.8 billion long-lasting insecticidal nets (LLINs) were distributed in Africa. While the insecticidal durability of LLINs is around 3 years, nets are commonly discarded 2 years post distribution.
Edith P. Madumla   +13 more
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Vector control for the chikungunya disease: chemical control versus biological control: a mathematical point of view. [PDF]

open access: yes, 2010
The aim of this talk is to present recent investigations on the Chikungunya Disease that hitted Réunion Island, a French territory in Indian Ocean, in 2005 and 2006. Chikungunya is a vectorborne Disease, usually localized in Asia and East-Africa. In 2005,
Dumont, Yves
core  

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