Results 61 to 70 of about 3,256,056 (300)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

How can onchocerciasis elimination in Africa be accelerated? Modelling the impact of increased ivermectin treatment frequency and complementary vector control [PDF]

Background: Great strides have been made toward onchocerciasis elimination by mass drug administration (MDA) of ivermectin. Focusing on MDA-eligible areas, we investigated where the elimination goal can be achieved by 2025 by continuation of current ...
Afework H Tekle, Alley, Annette C Kuesel, Basáñez, Basáñez, Basáñez, Bottomley, Boussinesq, Coffeng, Coffeng, Coffeng, Colebunders, Daniel A Boakye, Dyson, Filipe, GBD 2016 Disease and Injury Incidence and Prevalence Collaborators, Grace Fobi, Habbema, Honorat G M Zouré, Kaiser, Kamgno, Katabarwa, Kim, Little, Lont, Maria-Gloria Basáñez, Martin Walker, Matthews, Michel Boussinesq, Opoku, Plaisier, Plaisier, Plaisier, Sake J de Vlas, Samuel Wanji, Stolk, Stolk, Suzanne Verver, Tekle, Tekle, Traore, Turner, Turner, Turner, Turner, Walker, Walker, Walker, Walker, Wilma A Stolk, World Health Organization, World Health Organization, World Health Organization/African Programme for Onchocerciasis Control, World Health Organization/African Programme for Onchocerciasis Control, World Health Organization/African Programme for Onchocerciasis Control, World Health Organization/African Programme for Onchocerciasis Control, World Health Organization/African Programme for Onchocerciasis Control, Young Eun Kim, Zouré, Zouré   +59 more
core   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Ticks (Argasidae and Ixodidae) in Tehran Province, Central Iran: Distribution and Seasonal Activity

Veterinary Medicine International
Ticks are obligatory ectoparasites of vertebrates and can transmit pathogens, including: arboviruses, bacteria, and parasites to humans and animals worldwide.
Mojtaba Beik-Mohammadi, Maryam Tavassoli, Zakkyeh Telmadarraiy, Hassan Vatandoost, Farrokh Dabiri   +4 more
doaj   +1 more source

Isolation of Borrelia miyamotoi and other Borreliae using a modified BSK medium

Scientific Reports, 2021
Borrelia spirochetes are the causative agents of Lyme borreliosis (LB) and relapsing fever (RF). Despite the steady rise in infections and the identification of new species causing human illness over the last decade, isolation of borreliae in culture has
Adam J. Replogle, Christopher Sexton, John Young, Luke C. Kingry, Martin E. Schriefer, Marc Dolan, Tammi L. Johnson, Neeta P. Connally, Kerry A. Padgett, Jeannine M. Petersen   +9 more
doaj   +1 more source

Unified Direct-Flux Vector Control for AC Motor Drives [PDF]

The paper introduces a Unified Direct-Flux Vector Control scheme suitable for sinusoidal AC motor drives. The AC drives considered here are Induction Motor, Synchronous Reluctance and synchronous Permanent Magnet motor drives, including Interior and ...
Bojoi, R., Guglielmi, Paolo, Pellegrino, Gian-Mario Luigi   +2 more
core   +1 more source

The Biological Control of the Malaria Vector [PDF]

Toxins, 2012
The call for malaria control, over the last century, marked a new epoch in the history of this disease. Many control strategies targeting either the Plasmodium parasite or the Anopheles vector were shown to be effective. Yet, the emergence of drug resistant parasites and insecticide resistant mosquito strains, along with numerous health, environmental,
openaire   +3 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, Volume 20, Issue 6, Page 1453-1472, June 2026.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

12S rRNA based phylogeny and genetic diversity of Haemaphysalis spinigera, the primary vector for Kyasanur forest disease in India

Scientific Reports
Kyasanur Forest Disease (KFD), also known as Monkey Fever, is an important tick-borne viral infection in India. It is mainly transmitted by the hard tick vector, Haemaphysalis spinigera.
Nandhini Perumalsamy, Rohit Sharma, Ayyanar Elango, Shriram Ananganallur Nagarajan, Manju Rahi   +4 more
doaj   +1 more source

Loss-minimization control of vector-controlled induction motor drives [PDF]

[[abstract]]It is well known that the efficiency of induction motor drives under partial load can be improved via manipulation of its field. Among the numerous loss-minimization schemes proposed previously, the scheme that uses motor power factor as the ...
Yang, Sheng-ming
core   +1 more source