Results 81 to 90 of about 11,411,963 (305)

Evaluation of polyclonal antibodies raised in rabbits against dengue NS1 antigen

open access: yesScientific Reports
Dengue, a vector-borne disease caused by the dengue virus (DENV), is spread by Aedes mosquitoes like, Aedes aegypti and Aedes albopictus. In the absence of antiviral drugs or vaccines, dengue prevention is centered on mosquito vector control.
Philip Raj Abraham   +8 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Acute undifferentiated febrile illness in a traveler returning from Burkina Faso, West Africa to Puducherry, India- a case report

open access: yesBMC Infectious Diseases
Background Imported malaria remains a significant diagnostic challenge, particularly in regions approaching elimination. This case report is novel in its exploration of the complexities involved in diagnosing malaria imported from a high-endemic area to ...
Srikanth Srirama   +6 more
doaj   +1 more source

“In starvation, a bone can also be meat”: a mixed methods evaluation of factors associated with discarding of long-lasting insecticidal nets in Bagamoyo, Tanzania

open access: yesMalaria Journal, 2022
Background Between 2000 and 2019, more than 1.8 billion long-lasting insecticidal nets (LLINs) were distributed in Africa. While the insecticidal durability of LLINs is around 3 years, nets are commonly discarded 2 years post distribution.
Edith P. Madumla   +13 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Control of Chagas disease vectors [PDF]

open access: yesSalud Pública de México, 2003
Most Latin American countries are making dramatic progress in controlling Chagas disease, through a series of national and international initiatives focusing on elimination of domestic populations of Triatominae, improved screening of blood donors, and clinical support and treatment of persons infected with Trypanosoma cruzi.
JM Ramsey, CJ Schofield
openaire   +4 more sources

Vector Biology Boot Camp Toolkit [PDF]

open access: yes
The Vector Biology Boot Camp is a program offered by the Northeast Regional Center for Excellence in Vector-Borne Diseases to provide hands-on learning opportunities in vector surveillance and control program operations.
Northeast Regional Center for Excellence in Vector-Borne Diseases
core   +4 more sources

Insights into animal reservoir hosts for the circulation of Leishmania parasite in the sustainable phase of National Kala-azar Elimination Programme in India

open access: yesOne Health
Background: India, currently in the sustained phase of visceral leishmaniasis elimination, continues to face challenges due to reports of indigenous cases from emerging foci, detection of parasitic DNA in multiple sand fly species, and the potential ...
Prasanta Saini   +13 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Vector-Valued Control Variates

open access: yes, 2021
Control variates are variance reduction tools for Monte Carlo estimators. They can provide significant variance reduction, but usually require a large number of samples, which can be prohibitive when sampling or evaluating the integrand is computationally expensive.
Zhuo Sun   +2 more
openaire   +3 more sources

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