Results 91 to 100 of about 1,259,375 (343)

Determining cellular and biochemical function of a novel adhesion molecule in kidneys. [PDF]

, 2016
Acute kidney injury is an abrupt loss of kidney function that develops in short time with limited effective treatments other than kidney transplantation. We have identified TMIGD1 (Transmembrane immuno- globulin domain 1) as a novel receptor expressed in
Arafa, Emad
core   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

FEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue, Sandrine Picaud, Régine Hepp, Stéphanie Pons, Uwe Maskos, Bertrand Lambolez, Ludovic Tricoire   +6 more
wiley   +1 more source

Malnutrition exacerbates pathogenesis of Lutzomyia longipalpis sand fly-transmitted Leishmania donovani

Communications Biology
Visceral leishmaniasis (VL) is transmitted by Leishmania-infected sand fly bites and malnutrition is a known risk factor in human VL. Models using sand fly transmission or malnutrition promote parasite dissemination.
Eva Iniguez, Johannes Doehl, Pedro Cecilio, Tiago Donatelli Serafim, Caroline Percopo, Yvonne Rangel-Gonzalez, Somaditya Dey, Elvia J. Osorio, Patrick Huffcutt, Sofia Roitman, Claudio Meneses, Mara Short, Jesus G. Valenzuela, Peter C. Melby, Shaden Kamhawi   +14 more
doaj   +1 more source

Coinfection With Trypanosoma brucei Confers Protection Against Cutaneous Leishmaniasis

Frontiers in Immunology, 2018
Infection with certain bacteria, parasites, and viruses alters the host immune system to Leishmania major influencing disease outcome. Here, we determined the outcome of a chronic infection with Trypanosoma brucei brucei on cutaneous leishmaniasis (CL ...
Lais Pereira, Fabiano Oliveira, Shannon Townsend, Sonia Metangmo, Claudio Meneses, Ian N. Moore, Claudia I. Brodskyn, Jesus G. Valenzuela, Stefan Magez, Stefan Magez, Shaden Kamhawi   +10 more
doaj   +1 more source

Pathogenic Rickettsia spp. as emerging models for bacterial biology

Journal of Bacteriology
Our understanding of free-living bacterial models like Escherichia coli far outpaces that of obligate intracellular bacteria, which cannot be cultured axenically.
B. Sit, Rebecca L. Lamason
semanticscholar   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Overcoming insecticide resistance in Anopheles mosquitoes by using faster-acting solid forms of deltamethrin

Malaria Journal, 2023
Background Controlling malaria-transmitting Anopheles mosquitoes with pyrethroid insecticides is becoming increasingly challenging because of widespread resistance amongst vector populations.
Jessica Carson, Bryan Erriah, Stephania Herodotou, Alexander G. Shtukenberg, Leilani Smith, Svetlana Ryazanskaya, Michael D. Ward, Bart Kahr, Rosemary Susan Lees   +8 more
doaj   +1 more source

Virus-induced gene silencing database for phenomics and functional genomics in Nicotiana benthamiana [PDF]

, 2018
Virus-induced gene silencing (VIGS) is an important forward and reverse genetics method for the study of gene function in many plant species, especially Nicotiana benthamiana.
Chakravarthy, Suma, Chang, Junil, Del Pozo, Olga, Dinesh-Kumar, Savithramma P, Doraiswamy, Vanthana, Lee, Hee-Kyung, Liu, Yule, Martin, Gregory B, Mysore, Kirankumar S, Ramegowda, Venkategowda, Ryu, Choong-Min, Senthil-Kumar, Muthappa, Van Eck, Joyce, Wang, Keri, Wang, Mingyi, Xu, Ping   +15 more
core   +2 more sources

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

First report of N1575Y mutation in pyrethroid resistant Anopheles gambiae s.l. in Nigeria

Scientific African, 2020
In view of recent findings that codon 1575 mutation increases the L1014F-mediated resistance in Anopheles mosquitoes, we investigated the presence of this mutation in four States with intense pyrethroid resistance in Nigeria.
A. Tolulope Oyeniyi, A. Olufemi Adeogun, E. Taiwo Idowu, Bola Oboh, Abiodun Olakiigbe, Oluwakemi Adesalu, Tawakalitu Jimoh, T. Samson Awolola   +7 more
doaj   +1 more source