Results 71 to 80 of about 600,320 (348)

Functional characterization of AsOBP21f, an odorant-binding protein involved in human odor detection in the malaria vector Anopheles sinensis

Parasites & Vectors
Background Olfactory detection of host odors is fundamental to mosquito host-seeking behavior. Although the olfactory pathways of model species such as Anopheles gambiae have been well characterized, the molecular basis of human odor detection in ...
Fang Li, Ou Xu, Jiajia Zhou, Shulin He, Bin Chen, Zhengbo He   +5 more
doaj   +1 more source

[Molecular biology of adenoviral vectors].

Cirugia y cirujanos, 2007
Gene therapy is based on the use of DNA as a therapeutic material as an alternative therapeutic tool for treatment of human diseases. All proteins are codified into the DNA and several diseases result from the absence or aberrant expression of one or related genes, absence of expression of functional proteins, and alterations for regulation process in ...
Francisco, Martínez-Flores, Fausto Alejandro, Jiménez-Orozco, Hilda, Villegas-Castrejón   +2 more
openaire   +1 more source

Adeno-Associated Virus Genome Interactions Important for Vector Production and Transduction

Human Gene Therapy, 2020
Recombinant adeno-associated virus has emerged as one of the most promising gene therapy delivery vectors. Development of these vectors took advantage of key features of the wild-type adeno-associated virus (AAV), enabled by basic studies of the ...
Anna C. Maurer, M. Weitzman
semanticscholar   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Allelic diversity of merozoite surface protein genes (msp1 and msp2) and clinical manifestations of Plasmodium falciparum malaria cases in Aceh, Indonesia

Malaria Journal, 2021
Background The malaria control programme in Indonesia has successfully brought down malaria incidence in many parts in Indonesia, including Aceh Province.
Kurnia Fitri Jamil, Nandha Rizki Pratama, Sylvia Sance Marantina, Harapan Harapan, Muhammad Riza Kurniawan, Tjut Mariam Zanaria, Jontari Hutagalung, Ismail Ekoprayitno Rozi, Puji Budi Setia Asih, Supargiyono, Din Syafruddin   +10 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

The Spetses Summer Schools on Molecular and Developmental Biology [PDF]

, 2013
The Spetses Summer Schools - A Tribute to Marianne Grunberg-Manago - Founding and More than 40 Years of the School - How Spetses Summer Schools Were Run - Financing the Spetses Summer Schools - Past and Future of the Spetses Summer Schools - List
Feldmann, Horst
core   +1 more source

Phlebotomus duboscqi gut microbiota dynamics in the context of Leishmania infection

Frontiers in Immunology
IntroductionThe manipulation of the gut microbiota of disease vectors has emerged as a new approach to use in the integrated control of vector-borne diseases. For this purpose, a deep knowledge of their gut microbial communities is essential.
Kristina Tang, Yue Zhang, Claudio Meneses, Luana A. Rogerio, Laura Willen, Eva Iniguez, Shaden Kamhawi, Jesus G. Valenzuela, Fabiano Oliveira, Pedro Cecilio   +9 more
doaj   +1 more source

Coinfection With Trypanosoma brucei Confers Protection Against Cutaneous Leishmaniasis

Frontiers in Immunology, 2018
Infection with certain bacteria, parasites, and viruses alters the host immune system to Leishmania major influencing disease outcome. Here, we determined the outcome of a chronic infection with Trypanosoma brucei brucei on cutaneous leishmaniasis (CL ...
Lais Pereira, Fabiano Oliveira, Shannon Townsend, Sonia Metangmo, Claudio Meneses, Ian N. Moore, Claudia I. Brodskyn, Jesus G. Valenzuela, Stefan Magez, Stefan Magez, Shaden Kamhawi   +10 more
doaj   +1 more source

Pathogenic Rickettsia spp. as emerging models for bacterial biology

Journal of Bacteriology
Our understanding of free-living bacterial models like Escherichia coli far outpaces that of obligate intracellular bacteria, which cannot be cultured axenically.
B. Sit, Rebecca L. Lamason
semanticscholar   +1 more source