Results 61 to 70 of about 22,809 (305)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Speed and Current Control of Permanent Magnet Synchronous Motor Drive Using IMC Controllers

Advances in Electrical and Computer Engineering, 2012
The paper describes a current and speed control of the permanent magnet synchronous motor with vector control. For a current and speed controller, the Internal Model Control (IMC) method was chosen for its good tracking capability and demands on the ...
BRANDSTETTER, P., KRECEK, T.
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

A CORDIC like processor for computation of arctangent and absolute magnitude of a vector

, 2004
In this paper, we propose a CORDIC like algorithm for computing absolute magnitude of a vector and its corresponding phase angle. It eliminates scale factor compensation step as well as the addition/subtraction operation along the z datapath.
Troya, Alfonso, Jagdhold, Ulrich, Maharatna, Koushik, Krstic, Milos, Grass, Eckhard   +4 more
core  

A Cell Transterpreter [PDF]

, 2006
The Cell Broadband Engine is a hybrid processor which consists of a PowerPC core and eight vector co-processors on a single die. Its unique design poses a number of language design and implementation challenges.
Jacobsen, Christian L., Jadud, Matthew C., Dimmich, Damian J.   +2 more
core  

Large-Scale Visualization of Sparse Matrices [PDF]

, 2014
An efficient algorithm for parallel acquisition of visualization data for large sparse matrices is presented and evaluated both analytically and empirically.
Tvrdik, P., Dytrych, T., Langr, D., Simecek, I.   +3 more
core   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

16-channel photonic solver for optimization problems on a silicon chip

Chip
A programmable photonic solver for quadratic unconstrained binary optimization (QUBO) problems is demonstrated with a hybrid optoelectronic scheme, which consists of a photonic chip and an electronic driving board.
Jiayi Ouyang, Shengping Liu, Ziyue Yang, Wei Wang, Xue Feng, Yongzhuo Li, Yidong Huang   +6 more
doaj   +1 more source