Results 151 to 160 of about 1,757,511 (332)
Evaluation of Four Advanced Nozzle Concepts for Short Takeoff and Landing Performance [PDF]
Four advanced nozzle concepts were tested on a canard-wing fighter in the Langley 14- by 22-Foot Subsonic Tunnel. The four vectoring-nozzle concepts were as follows: (1) an axisymmetric nozzle (AXI); (2) an asymmetric, load balanced exhaust nozzle (ALBEN)
Kemmerly, Guy T. +2 more
core +1 more source
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
FEBS Open Bio, EarlyView.Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
Investigation of ground effects on large and small scale models of a three fan V/STOL aircraft configuration [PDF]
Induced lift of a subsonic, three fan, lift/cruise, V/STOL aircraft configuration was investigated using scale modes of a multimission aircraft whose design incorporates a nose mounted lift fan and two lift/cruise units located over the wing ...
Carter, T. D. +2 more
core +1 more source
Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion
FEBS Open Bio, EarlyView.Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng +2 more
wiley +1 more source
Generalized Design, Modeling and Control Methodology for a Snake-like Aerial Robot. [PDF]
Sensors (Basel), 2023 Zhao M, Nishio T.
europepmc +1 more source
Conceptual design, evaluation and research identification for Remote Augmented Propulsive Lift Systems (RALS) with ejectors for VTOL aircraft [PDF]
Ejector concepts for use with a remote augmented lift system (RALS) exhaust nozzle were studied. A number of concepts were considered and three were selected as having the greatest promise of providing the desired aircraft and exhaust gas cooling and ...
Konarski, M. +2 more
core +1 more source
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
FEBS Open Bio, EarlyView.The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
Regulatory observer: international and Australian regulatory developments and decisions [PDF]
Provides information and updates about international (focusing on the OECD) and Australian regulatory developments and decisions. Summary In this issue: European Commission funding for transport infrastructure International regulatory round-up ...
core
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source