Results 51 to 60 of about 10,499 (305)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Vectorization in Analyzing 2D/3D Data [PDF]
, 2016 : Vectorization is an important process in the fields of graphics and image processing. In computer-aided design (CAD), drawings are scanned, vectorized and written as CAD files in a process called paper-to-CAD conversion or drawing conversion.
core
Vectorization of CMSSW offline software
, 2023 Vectorization in CMSSW applicationsThe CMS experiment has been utilizing vectorization, or SIMD, in parts of its data processing applications for over a decade. On x86 platforms the vectorization level is still SSE3.
Gartung, Patrick Elmo
core +1 more source
Hierarchical vectorization for facial images
Computational Visual Media, 2023 The explosive growth of social media means portrait editing and retouching are in high demand. While portraits are commonly captured and stored as raster images, editing raster images is non-trivial and requires the user to be highly skilled.
Qian Fu, Linlin Liu, Fei Hou, Ying He
doaj +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Известия ТИНРОUnmanned aerial counting of pacific salmon in the rivers of the Okhotsk district (Khabarovsk Region) in 2021–2023 is analyzed. Estimates of the spawning redds number and the spawners abundance are presented for the monitoring sites.
D. V. Kotsyuk +2 more
doaj +1 more source
Automatic Vector-Based Road Structure Mapping Using Multibeam LiDAR
Remote Sensing, 2019 The high-definition map (HD-map) of road structures is crucial for the safe planning and control of autonomous vehicles. However, generating and updating such maps requires intensive manual work.
Junqiao Zhao +5 more
doaj +1 more source