Results 61 to 70 of about 10,499 (305)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Polyhedral-Model Guided Loop-Nest Auto-Vectorization

open access: yes, 2009
International audienceOptimizing compilers apply numerous inter- dependent optimizations, leading to the notoriously difficult phase-ordering problem -- that of deciding which trans- formations to apply and in which order.
Zaks, Ayal   +9 more
core   +1 more source

Automatic Classification of Ukrainian Texts by Functional Styles

open access: yesInformation Technologies and Systems
The proposed multilevel method for classifying Ukrainian texts by functional style combines statistical analysis, keyword analysis, and contextual analysis based on the BERT model, which accounts for semantic and contextual dependencies in the text ...
M.A. Muzychuk, T.M. Zabolotnia
doaj   +1 more source

Taxonomy of Vectorization Patterns of Programming for FIR Image Filters Using Kernel Subsampling and New One

open access: yesApplied Sciences, 2018
This study examines vectorized programming for finite impulse response image filtering. Finite impulse response image filtering occupies a fundamental place in image processing, and has several approximated acceleration algorithms.
Yoshihiro Maeda   +2 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Vectorization for Java

open access: yes, 2010
International audienceJava is one of the most popular programming languages in today's software development, but the adoption of Java in some areas like high performance computing, gaming, and media processing is not as universal as in general-purpose ...
Buqi Cheng   +9 more
core   +1 more source

Intermediate Representations for Vectorization of Stylized Images

open access: yes, 2020
This paper presents a new approach for the vectorization of stylized images using intermediate data representations to interface image stylization and vectorization techniques.
Döllner, Jürgen   +3 more
core   +1 more source

Vectorization of Loops with Conditional Operations by Combining Vector Masks

open access: yesСовременные информационные технологии и IT-образование
The article is devoted to the problem of increasing the efficiency of vectorization for calculations on real numbers. When performing calculations, several similar scalar operations can be combined into a single vector command, significantly increasing ...
Alexey Rybakov
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

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