Results 101 to 110 of about 4,245,387 (333)
Malaria JournalBackground Anopheles kleini is a competent vector mainly observed in the northern, malaria-risk areas of the Republic of Korea (ROK). In this study, the population genetic structure of An.
Haneul Jung +4 more
doaj +1 more source
, 2005 Courses in introductory special and general relativity have increasingly become part of the curriculum for upper-level undergraduate physics majors and master's degree candidates. One of the topics rarely discussed is symmetry, particularly in the theory
Adler R. +8 more
core +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Parasites & VectorsBackground Toxoplasma gondii and Neospora caninum are closely related protozoan parasites that are considered important causes of abortion in livestock, causing huge economic losses. Hunan Province ranks 12th in the production of beef and mutton in China.
Xi-Long Yi +9 more
doaj +1 more source
Onderstepoort Journal of Veterinary Research, 2016 An unpredicted outbreak of African animal trypanosomosis or nagana in 1990 in north-eastern KwaZulu-Natal necessitated an emergency control programme, utilising the extensive cattledipping system in the area, as well as a reassessment of the tsetse and ...
Chantel J. de Beer +10 more
doaj +1 more source
Sparse Overcomplete Word Vector Representations
, 2015 Current distributed representations of words show little resemblance to theories of lexical semantics. The former are dense and uninterpretable, the latter largely based on familiar, discrete classes (e.g., supersenses) and relations (e.g., synonymy and ...
Dyer, Chris +4 more
core +1 more source
Advances in Non-Viral DNA Vectors for Gene Therapy
Genes, 2017 Uses of viral vectors have thus far eclipsed uses of non-viral vectors for gene therapy delivery in the clinic. Viral vectors, however, have certain issues involving genome integration, the inability to be delivered repeatedly, and possible host ...
Cinnamon L. Hardee +3 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source