Results 21 to 30 of about 2,628,537 (340)

Microbial Pre-exposure and Vectorial Competence of Anopheles Mosquitoes

Frontiers in Cellular and Infection Microbiology, 2017
Anopheles female mosquitoes can transmit Plasmodium, the malaria parasite. During their aquatic life, wild Anopheles mosquito larvae are exposed to a huge diversity of microbes present in their breeding sites.
Constentin Dieme, Constentin Dieme, Brice Rotureau, Christian Mitri, Christian Mitri   +4 more
doaj   +1 more source

Membrane Chromatography-Based Downstream Processing for Cell-Culture Produced Influenza Vaccines

Vaccines, 2022
New influenza strains are constantly emerging, causing seasonal epidemics and raising concerns to the risk of a new global pandemic. Since vaccination is an effective method to prevent the spread of the disease and reduce its severity, the development of
Zeyu Yang, Xingge Xu, Cristina A. T. Silva, Omar Farnos, Alina Venereo-Sanchez, Cécile Toussaint, Shantoshini Dash, Irene González-Domínguez, Alice Bernier, Olivier Henry, Amine Kamen   +10 more
doaj   +1 more source

Past and future spread of the arbovirus vectors Aedes aegypti and Aedes albopictus

Nature Microbiology, 2019
The global population at risk from mosquito-borne diseases—including dengue, yellow fever, chikungunya and Zika—is expanding in concert with changes in the distribution of two key vectors: Aedes aegypti and Aedes albopictus.
M. Kraemer, R. Reiner, O. Brady, J. Messina, M. Gilbert, D. Pigott, D. Yi, Kimberly B Johnson, Lucas Earl, L. Marczak, S. Shirude, Nicole Davis Weaver, D. Bisanzio, T. Perkins, S. Lai, Xin Lu, Peter Jones, G. Coelho, R. G. Carvalho, W. Van Bortel, Cedric Marsboom, G. Hendrickx, F. Schaffner, C. G. Moore, H. Nax, Linus Bengtsson, Erik Wetter, A. Tatem, J. Brownstein, David L. Smith, L. Lambrechts, S. Cauchemez, C. Linard, Nuno R. Faria, O. Pybus, T. Scott, Qiyong Liu, Hongjie Yu, G. Wint, Simon Iain Hay, N. Golding   +40 more
semanticscholar   +1 more source

Human Immune Responses to Adeno-Associated Virus (AAV) Vectors

Frontiers in Immunology, 2020
Recombinant adeno-associated virus (rAAV) vectors are one of the most promising in vivo gene delivery tools. Several features make rAAV vectors an ideal platform for gene transfer. However, the high homology with the parental wild-type virus, which often
G. Ronzitti, D. Gross, F. Mingozzi
semanticscholar   +1 more source

Genome-wide transcriptome profiling and spatial expression analyses identify signals and switches of development in tapeworms

EvoDevo, 2018
Background Tapeworms are agents of neglected tropical diseases responsible for significant health problems and economic loss. They also exhibit adaptations to a parasitic lifestyle that confound comparisons of their development with other animals ...
Peter D. Olson, Magdalena Zarowiecki, Katherine James, Andrew Baillie, Georgie Bartl, Phil Burchell, Azita Chellappoo, Francesca Jarero, Li Ying Tan, Nancy Holroyd, Matt Berriman   +10 more
doaj   +1 more source

Sialotranscriptomics of Rhipicephalus zambeziensis reveals intricate expression profiles of secretory proteins and suggests tight temporal transcriptional regulation during blood-feeding

Parasites & Vectors, 2017
Background Ticks secrete a diverse mixture of secretory proteins into the host to evade its immune response and facilitate blood-feeding, making secretory proteins attractive targets for the production of recombinant anti-tick vaccines.
Minique Hilda de Castro, Daniel de Klerk, Ronel Pienaar, D Jasper G Rees, Ben J Mans   +4 more
doaj   +1 more source

The global distribution of the arbovirus vectors Aedes aegypti and Ae. albopictus

eLife, 2015
Dengue and chikungunya are increasing global public health concerns due to their rapid geographical spread and increasing disease burden. Knowledge of the contemporary distribution of their shared vectors, Aedes aegypti and Aedes albopictus remains ...
Moritz U. G. Kraemer, Marianne E. Sinka, Kirsten A. Duda, A. Mylne, F. Shearer, Christopher M. Barker, Chester G. Moore, R. G. Carvalho, Giovanini E. Coelho, W. van Bortel, Guy Hendrickx, Francis Schaffner, I. Elyazar, H. Teng, Oliver J. Brady, J. Messina, D. Pigott, Thomas W. Scott, David L. Smith, G. W. Wint, N. Golding, Simon I. Hay   +21 more
semanticscholar   +1 more source

The first detected airline introductions of yellow fever mosquitoes (Aedes aegypti) to Europe, at Schiphol International airport, the Netherlands

Parasites & Vectors, 2017
Background Air-borne introduction of exotic mosquitoes to Schiphol airport in the Netherlands has been considered plausible based upon findings of mosquitoes in aircraft cabins during 2008, 2010 and 2011.
A. Ibañez-Justicia, A. Gloria-Soria, W. den Hartog, M. Dik, F. Jacobs, A. Stroo   +5 more
doaj   +1 more source

Clinical use of lentiviral vectors

Leukemia, 2018
Viral vectors provide an efficient means for modification of eukaryotic cells, and their use is now commonplace in academic laboratories and industry for both research and clinical gene therapy applications.
M. Milone, U. O’Doherty
semanticscholar   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source