Results 231 to 240 of about 717,961 (381)

Uncoupling the roles of VEGF [PDF]

, 2011
Leonie Welberg
openalex   +1 more source

Novel Needle for Intravitreal Injections Does Not Affect Biological Activity of Anti-VEGF Drugs. [PDF]

Clin Ophthalmol
Lytvynchuk L, Nolte KL, Fuezy I, Zhou W, Deissler H, Deissler HL.   +5 more
europepmc   +1 more source

Single‐Nucleus RNA Sequencing Reveals Mid‐Gestational Neurodevelopment Features in the Superior Temporal Plane from Fetuses with Nonsyndromic Cleft Lip and Palate

Advanced Science, EarlyView.
Single‐nucleus RNA sequencing of mid‐gestation brains from fetuses with nonsyndromic cleft lip and palate reveals major disruptions in cell composition, cell‐to‐cell signaling, and gene regulation. The transcription factor MEF2C is identified as a central regulator of these changes and shows that lowering MEF2C impairs synapse formation, linking cleft ...
Liu‐Lin Xiong, Xin‐Wei Huang, Qiu‐Xia Xiao, Ying‐Gang Zheng, Hao‐Yue Qin, Chang‐Le Fang, Li Chen, Ruo‐Lan Du, Qiu‐Lin Wang, Li‐Ren Huangfu, Ye‐Qing Fei, Yang‐Yang Zhao, Chen‐Yang Zhai, Ze‐Mian Chen, Shi‐Kun Yuan, Yu‐Ji Zhou, Xing‐Man He, Ting‐Ting Zhi, Xiao‐He Tian, Ting‐Hua Wang   +19 more
wiley   +1 more source

Supplementary Figure 4 from A Novel Inhibitor of c-Met and VEGF Receptor Tyrosine Kinases with a Broad Spectrum of <i>In Vivo</i> Antitumor Activities

, 2023
Yoshiko Awazu, Kazuhide Nakamura, Akio Mizutani, Yuichi Kakoi, Hidehisa Iwata, Seiji Yamasaki, Naoki Miyamoto, Shinichi Imamura, Hiroshi Miki, Akira Hori   +9 more
openalex   +1 more source

Nicotine-Induced VEGF Levels in NSCLC Cells Are Modulated by PKA, Hyaluronan, and p53. [PDF]

Int J Mol Sci
Wozniak C, Cobos A, Sabri A, Goel S, Lopo B, Sarofim S, Chutipassakul C, Guthrie J, Heyl D, Evans HG.   +9 more
europepmc   +1 more source

Continuous Suppression of Pathological Retinal and Choroidal Neovascularization in Cynomolgus Monkeys via Noninvasive Ophthalmic Delivery of a Novel Anti‐VEGFA Nanobody and Proprietary Penetratin Analog Formulation

Advanced Science, EarlyView.
Pathological retinal/choroidal neovascularization drives vision loss in DR and AMD. Current anti‐VEGF injections, while effective, require invasive, frequent administration. Pene/LQ015, is developed a novel topical anti‐VEGFA nanobody formulation achieving therapeutic intraocular levels through penetratin analog‐enhanced delivery.
Chong Chen, Min Zhu, Xingyan Fan, Kangjia Lv, Kuan Jiang, Yuchen Zhang, Haoliang Zhang, Xinming Qi, Benjamin TK Lee, Yakun Wan, Gang Wei, Kun Liu, Xun Xu   +12 more
wiley   +1 more source

Insights from pharmacovigilance databases, clinical cohorts and preclinical models into VEGF(R) inhibitor-induced arthritis in cancer. [PDF]

Commun Med (Lond)
Xu L, Lin A, Li Z, Shen J, Chi H, Wong HZH, Zhang J, Wang Q, Xu J, Zhang P, Luo P.   +10 more
europepmc   +1 more source

Targeting VEGF and Its Receptors for the Treatment of Osteoarthritis and Associated Pain

Journal of Bone and Mineral Research, 2016
J. L. Hamilton, Masashi Nagao, B. Levine, Di Chen, B. Olsen, H. Im   +5 more
semanticscholar   +1 more source

CircSMEK1 Suppresses HCC via the hnRNPK‐IGF2‐AKT Axis: A Diagnostic Biomarker and Therapeutic Target

Advanced Science, EarlyView.
CircSMEK1 is downregulated in MASH/HCC and predicts poor prognosis. It suppresses tumor progression by promoting hnRNPK ubiquitination and inhibiting the IGF2/PI3K/AKT axis, while its loss activates immunosuppressive cancer‐associated fibroblasts. Serum circSMEK1 serves as a non‐invasive diagnostic biomarker, and its restoration potently inhibits HCC ...
Peilan Guo, Xiaomeng Jia, Shenghong Wang, Xinyu Li, Yajing Liu, Lisen Lin, Zhengkun Wang, Fujun Liu, Slawomir Wolczynski, Nafis Rahman, Jie Gao, Xuguang Du, Suk‐Ying Tsang, Jiali Liu, Wei Song, Xiangdong Li   +15 more
wiley   +1 more source

Breaking the barrier: a guidelines-based review of antiangiogenesis drug resistance in pediatric cancer therapy. [PDF]

Clin Exp Pediatr
Shakibazad N, Shahriari M, Ramzi M.
europepmc   +1 more source