Results 231 to 240 of about 539,443 (278)

Meningeal lymphatic-associated brain swelling in acute stroke. [PDF]

PLoS One
Patil RM, Back DB, Hamanaka G, Desai R, Hayakawa A, Chan SJ, Ahn BJ, Pignataro G, Hayakawa K, Esposito E.   +9 more
europepmc   +1 more source

Self‐Adaptive Allantoin@ZIF8 Nanocomposite Hydrogel with Resveratrol Synergy for MRSA‐Infected Wound Regeneration

Advanced Science, EarlyView.
Based on allantoin‐loaded ZIF8 nanoparticles (Alla@ZIF8) and methacrylated quaternary ammonium carboxymethyl chitosan/resveratrol composite hydrogels (RMQCC), an adaptive multifunctional hydrogel system (Alla@ZIF8‐Gel) was constructed and confirmed to induce the healing of MRSA‐infected wounds via suppressing bacterial proliferation, alleviating ...
Yongjie Zhu, Dun Liu, Mengran Zhao, Xinyi Jian, Enuo Peng, Xingping Zhao, Zezhang Zhu, Bolin Tang, Benlong Shi   +8 more
wiley   +1 more source

Comparative evaluation of stability, efficacy, and sterility in five repackaged intravitreal anti-vascular endothelial growth factor medications. [PDF]

Sci Rep
Thunwiriya P, Phetruen T, Chaiwijit P, Tonawannakorn C, Dekham K, Thadtapong N, Chaturongakul S, Charoensawan V, Chanarat S, Pakotiprapha D, Hanutsaha P.   +10 more
europepmc   +1 more source

Dissecting VEGFR-2 and VEGFR-3 function : VEGFR-3 mediates lymphangiogenic signals [PDF]

, 2002
Veikkola, Tanja
core  

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Different types of exercise and myocardial angiogenesis regulation: A scoping review of cardiac-specific evidence in animal models. [PDF]

Physiol Rep
Karisa P, Sylviana N, Rosdianto AM, Goenawan H, Syamsunarno MRAA, Setiawan.   +5 more
europepmc   +1 more source

Targeting WTAP/ROR1/WNT5A‐Mediated Crosstalk Between Glioma Stem Cells and Macrophages to Normalize Tumor Vasculature and Enhance Chemotherapy

Advanced Science, EarlyView.
In hypoxic microenvironment, WNT5A is predominantly secreted by tumor‐associated macrophages. Hypoxia‐induced WTAP mediates ROR1 stability by m6A modifications in a HuR‐dependent manner in Glioma stem cells (GSCs). WNT5A activates the WNT pathway via ROR1 binding on GSCs, driving glioma‐derived endothelial cells (GDECs) differentiation.
Xiaoyong Chen, Bo Pang, Yun Liu, Jiangwei Wang, Lanhui Zheng, Yuzhou Chang, Yingxuan Sun, Haoyuan Sun, Huiyuan Chen, Jiawei Cai, Zanyi Wu, Qing Chang, Yongzhi Wang, Dezhi Kang, Tao Jiang, Ruichao Chai   +15 more
wiley   +1 more source

Longitudinal Assessment of an 800 µg Dose of HEBERSaVax in Non-Human Primates over Six Months. [PDF]

Vaccines (Basel)
Canaán-Haden C, Gonzalez-Moya I, Bequet-Romero M, Cabanillas-Bernal O, Martínez-Castillo R, Cerioli-Pentón C, Chavez-Castro N, Ayala-Ávila M, Castro-Velazco J, Licea-Navarro AF, Morera-Díaz Y.   +10 more
europepmc   +1 more source

Glutamine Deprivation Triggers Tribbles Homolog 3 Dependent G‐Quadruplex Resolution to Maintain DNA Repair and Tumor Survival

Advanced Science, EarlyView.
Glutamine deprivation triggers transient DNA damage yet activates adaptive repair in hepatocellular carcinoma cells. We identify TRIB3 as a stress‐induced nuclear scaffold that associates with DDX5 and G‐quadruplex DNA atBRCA1 andRAD51AP1 promoters. TRIB3 loss increases G4 accumulation, suppresses HR gene transcription, elevates γ‐H2A.X, and sensitizes
Qiang Ji, Xuedan Sun, Zhangran Sun, Mengfan Li, Xinyu Cheng, Shuai Tian, Rick F. Thorne, Jinming Li, Guangzhi Liu, Mian Wu, Xiaoying Liu   +10 more
wiley   +1 more source

Nintedanib Eye Drops Inhibit Alkali Burn-Induced Corneal Neovascularization Via RAP1/MEK/ERK Signaling Pathway. [PDF]

Invest Ophthalmol Vis Sci
Li J, Zhang G, Li J, Liu R, Zhu L, Li J, Li Z.   +6 more
europepmc   +1 more source