Results 1 to 10 of about 2,542,305 (231)
The presence of VEGF receptors on the luminal surface of endothelial cells affects VEGF distribution and VEGF signaling. [PDF]
PLoS Computational Biology, 2009 Vascular endothelial growth factor (VEGF) is a potent cytokine that binds to specific receptors on the endothelial cells lining blood vessels. The signaling cascade triggered eventually leads to the formation of new capillaries, a process called ...
Marianne O Stefanini +3 more
doaj +5 more sources
Zebrafish VEGF receptors: a guideline to nomenclature. [PDF]
PLoS Genetics, 2008 In placental mammals (eutherians), there exist three paralogous genes of the vascular endothelial growth factor (VEGF) receptor family, namely FLT1 (also named VEGFR1), KDR (also named FLK1 and VEGFR2), and FLT4 (also named VEGFR3).
Jeroen Bussmann +4 more
doaj +7 more sources
A class of extracellular vesicles from breast cancer cells activates VEGF receptors and tumour angiogenesis. [PDF]
Nat Commun, 2017 Non-classical secretory vesicles, collectively referred to as extracellular vesicles (EVs), have been implicated in different aspects of cancer cell survival and metastasis.
Feng Q +8 more
europepmc +2 more sources
Discovery of pan-VEGF inhibitory peptides directed to the extracellular ligand-binding domains of the VEGF receptors. [PDF]
Sci Adv, 2016 Extracellular ligand-binding inhibitors of receptor tyrosine kinases (eTKIs) in angiogenesis. Receptor tyrosine kinases (RTKs) are key molecules in numerous cellular processes, the inhibitors of which play an important role in the clinic.
Michaloski JS +4 more
europepmc +2 more sources
PLoS ONE, 2013 Vascular endothelial growth factor (VEGF) is up-regulated during mesothelial to mesenchymal transition (MMT) and has been associated with peritoneal membrane dysfunction in peritoneal dialysis (PD) patients.
María Luisa Pérez-Lozano +9 more
doaj +2 more sources
Functional VEGF and VEGF receptors are expressed in human medulloblastomas [PDF]
Neuro-Oncology, 2007 Vascular endothelial growth factor (VEGF) is one of the key regulators of tumor neoangiogenesis. It acts through two types of high-affinity tyrosine kinase receptors (VEGF receptor-1 [VEGFR-1]/fms-related tyrosine kinase 1 [Flt-1] and VEGFR-2/kinase domain receptor [KDR]) expressed on endothelial cells.
M. Liliana Slongo +8 more
openalex +4 more sources
VER/VEGF receptors regulate AMPA receptor surface levels and glutamatergic behavior. [PDF]
PLoS Genet, 2021 Luth ES +6 more
europepmc +3 more sources
Fox(y) regulators of VEGF receptors. [PDF]
Circ Res, 2014 Vascular development is a multistep process that initially involves vasculogenesis, the process of de novo formation of the primitive vasculature from mesodermal precursors, and angiogenesis, that involves sprouting and remodeling of the primitive vasculature.1 This is followed by vascular fate specification steps that define formation of arterial ...
Ricard N, Simons M.
europepmc +4 more sources
VEGF, its receptors and the Tie receptors in recurrent miscarriage [PDF]
Molecular Human Reproduction, 2000 The aetiology of recurrent miscarriage (at least three consecutive miscarriages) usually remains unsolved. The vascular endothelial growth factor (VEGF) family of proteins, together with their receptors and the Tie (tyrosine kinase with immunoglobulin and epidermal growth factor homology domains) receptors, are crucial for embryonic development ...
Piia Vuorela +3 more
openalex +3 more sources
Structure and function of VEGF receptors
IUBMB Life, 2009 AbstractVascular endothelial growth factors (VEGFs) regulate blood and lymphatic vessel development and homeostasis. VEGFs are predominantly produced by endothelial, hematopoietic, and stromal cells in response to hypoxia and upon stimulation by growth factors such as transforming growth factor β (TGFβ), interleukins, or platelet‐derived growth factors
E. Stuttfeld, K. Ballmer-Hofer
semanticscholar +3 more sources