Results 1 to 10 of about 2,552,796 (291)

Serum Levels of VEGF-A and Its Receptors in Patients in Different Phases of Hemorrhagic and Ischemic Strokes

open access: yesCurrent Issues in Molecular Biology, 2022
Vascular endothelial growth factors (VEGFs) are important regulators of angiogenesis, neuroprotection, and neurogenesis. Studies have indicated the association of VEGF dysregulation with the development of neurodegenerative and cerebrovascular diseases ...
Anastasiya S. Babkina   +7 more
doaj   +1 more source

Vascular endothelial growth factor regulates osteoblast survival – evidence for an autocrine feedback mechanism

open access: yesJournal of Orthopaedic Surgery and Research, 2009
Background Apoptosis of osteoblasts and osteoclasts regulates bone homeostasis. Skeletal injury in humans results in 'angiogenic' responses primarily mediated by vascular endothelial growth factor(VEGF), a protein essential for bone repair in animal ...
Street John, Lenehan Brian
doaj   +1 more source

EXPRESSION OF THE VASCULAR ENDOTHELIAL GROWTH FACTOR AND ITS RECEPTORS (VEGFR-1 AND VEGFR-2) IN PRIMARY TUMOR CELLS IN PATIENTS WITH RENAL CANCER

open access: yesСибирский онкологический журнал, 2021
Purpose: to study the expression of vascular endothelial growth factor (vegf-a) and its receptors (vegfr-1 and vegfr-2) in renal cell carcinoma (rcc) cells and assess the effect of the expression levels of these markers on the tumor characteristics and ...
D. A. Khochenkov   +7 more
doaj   +1 more source

Vascular Endothelial Growth Factor Signaling in Models of Oxygen-Induced Retinopathy: Insights Into Mechanisms of Pathology in Retinopathy of Prematurity

open access: yesFrontiers in Pediatrics, 2021
Retinopathy of prematurity (ROP) is a leading cause of blindness in children worldwide. Blindness can occur from retinal detachment caused by pathologic retinal angiogenesis into the vitreous, termed intravitreal neovascularization (IVNV).
Aniket Ramshekar, M. Elizabeth Hartnett
doaj   +1 more source

Gene Expression Analysis of VEGF and Its Receptors and Assessment of Its Serum Level in Unexplained Recurrent Spontaneous Abortion [PDF]

open access: yesCell Journal, 2015
Objective: Unexplained recurrent spontaneous abortion (URSA) is one of the main complications of pregnancy which is usually defined as three or more consecutive pregnancy losses before the 20th week of gestation without a known cause.
Elham Amirchaghmaghi   +5 more
doaj  

A Hybrid Model of the Role of VEGF Binding in Endothelial CellMigration and Capillary Formation

open access: yesFrontiers in Oncology, 2013
Vascular endothelial growth factor (VEGF) is the most studied family of soluble secreted mediators of endothelial cell migration, survival and proliferation.
Harsh eJain, Trachette eJackson
doaj   +1 more source

Structural Basis for Vascular Endothelial Growth Factor Receptor Activation and Implications for Disease Therapy

open access: yesBiomolecules, 2020
Vascular endothelial growth factors (VEGFs) bind to membrane receptors on a wide variety of cells to regulate diverse biological responses. The VEGF-A family member promotes vasculogenesis and angiogenesis, processes which are essential for vascular ...
Faheem Shaik   +5 more
doaj   +1 more source

Compartment model predicts VEGF secretion and investigates the effects of VEGF Trap in tumor-bearing mice

open access: yesFrontiers in Oncology, 2013
Angiogenesis, the formation of new blood vessels from existing vasculature, is important in tumor growth and metastasis. A key regulator of angiogenesis is vascular endothelial growth factor (VEGF), which has been targeted in numerous anti-angiogenic ...
Stacey D Finley   +2 more
doaj   +1 more source

VEGF-A, VEGF-C, and VEGF-D in Colorectal Cancer Progression

open access: yesNeoplasia: An International Journal for Oncology Research, 2001
We aimed to assess the relationship of the angiogenic cytokines VEGF-A, VEGF-C, and VEGF-D and their receptors VEGFR-2 and VEGFR-3 in the adenomacarcinoma sequence and in metastatic spread of colorectal cancer (CRC).
Mark L. George   +6 more
doaj   +1 more source

Peculiarities of serum levels of vascular growth factor and its receptors in dialysis patients

open access: yesУкраїнський Журнал Нефрології та Діалізу, 2022
Recent research has shown that VEGF may influence the condition and survival of patients with chronic kidney disease (CKD), including those treated with dialysis procedures.
V. Driianska   +5 more
doaj   +1 more source

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