Results 221 to 230 of about 2,468,898 (371)

A novel Pyroptosis‐related long non‐coding RNA signature for predicting the prognosis and immune landscape of head and neck squamous cell carcinoma

Cancer Medicine, Volume 11, Issue 24, Page 5097-5112, December 2022., 2022
our findings robustly demonstrate that our constructed prlncRNA signature could serve as an efficient indicator of prognosis, immunotherapy response, and chemosensitivity for HNSCC patients. Abstract Background Pyroptosis plays an essential function in carcinogenesis and the antitumor immune response.
Chongchang Zhou, Yiming Shen, Yangli Jin, Zhisen Shen, Dong Ye, Yi Shen, Hongxia Deng   +6 more
wiley   +1 more source

Inhibition of retinal neovascularisation by gene transfer of soluble VEGF receptor sFlt-1 [PDF]

, 2002
James Bainbridge, Ajay Mistry, M. De Alwis, Ewa Paleolog, Andrew H. Baker, AJ Thrasher, Robin R. Ali   +6 more
openalex   +1 more source

Neoadjuvant Chemotherapy With Cisplatin Up‐Regulates GSDMD to Enhance Oral Squamous Cell Carcinoma Metastasis Through MMP14‐Mediated EMT Activation

Advanced Science, EarlyView.
Oral squamous cell carcinoma cells exhibit upregulated expression of GSDMD upon exposure to low‐dose cisplatin chemotherapy, which subsequently interacts with MMP14 through its N‐terminal domain, activating the epithelial‒mesenchymal transition (EMT) process and promoting the lymph node metastasis of oral squamous cell carcinoma.
Zixian Huang, Qiming Jiang, Qianyu Zhang, Nan Lu, Xi Rui, Rui Chen, Yan Wang, Yuepeng Wang, Xiaoding Xu, Zhiquan Huang   +9 more
wiley   +1 more source

Advances in exosome biomarkers for cervical cancer

Cancer Medicine, Volume 11, Issue 24, Page 4966-4978, December 2022., 2022
Cancer‐derived exosomes may promote CC metastasis by boosting cellular epithelial‐mesenchymal transformation (EMT), controlling the proliferation, invasion, or migration of cancer cells, as well as influencing immune escape and aiding angiogenesis.
Zihan Ran, Shaobo Wu, Zijng Ma, Xiuwen Chen, Jing Liu, Jingcheng Yang   +5 more
wiley   +1 more source

VEGF-mediated angiogenesis is impaired by angiotensin type 1 receptor blockade in cardiomyopathic hamster hearts [PDF]

, 2003
Tadamichi Shimizu, Hiroshi Okamoto, Satoru Chiba, Yasuhisa Matsui, T. Sugawara, M AKINO, Nan Ji, Hideki Kumamoto, Hisao Onozuka, Takeshi Mikami   +9 more
openalex   +1 more source

Bacterial Capture‐Killing Capsules with Remodeling Bone Immune Microenvironment for the Effective Treatment of Osteomyelitis

Advanced Science, EarlyView.
The PC‐O@TOB capsules are designed to exhibit bactericidal effects, regulate the bone immune microenvironment by promoting M2 macrophage polarization, eliminate excessive ROS, and enhance bone regeneration, providing a novel multi‐dimensional approach for the treatment of osteomyelitis.
Dong Yang, Chang Shu, Chengwei Xu, Xingjie Zan, Shaoyin Wei, Chenglong Wang, Lianxin Li   +6 more
wiley   +1 more source

Ultrastructural Localization of the Vascular Permeability Factor/Vascular Endothelial Growth Factor (VPF/VEGF) Receptor-2 (FLK-1, KDR) in Normal Mouse Kidney and in the Hyperpermeable Vessels Induced by VPF/VEGF-expressing Tumors and Adenoviral Vectors

, 2000
Dian Feng, Janice A. Nagy, Rolf A. Brekken, Ånna Pettersson, E J Manseau, Kathryn Pyne, Richard C. Mulligan, Philip E. Thorpe, Harold F. Dvorak, Ann M. Dvořàk   +9 more
openalex   +1 more source

Kaposi's sarcoma associated herpesvirus G protein-coupled receptor immortalizes human endothelial cells by activation of the VEGF receptor-2/ KDR [PDF]

, 2003
Carlos Bais, Albert Van Geelen, Pîlar Eroles, Agata D'Agostino Mutlu, Chiara Chiozzini, Sérgio Dias, Roy L. Silverstein, Shahin Rafii, Enrique A. Mesri   +8 more
openalex   +1 more source

Microenvironmental Modulation for Therapeutic Efficacy of Extracellular Vesicles

Advanced Science, EarlyView.
Recent studies highlighted the heterogeneity of EVs and the influence of microenvironmental signals on their therapeutic efficacy. This review offers a comprehensive overview of strategies and mechanisms to optimize the therapeutic efficacy of EVs through physical, biochemical, and mechanical modulation.
Bilu Xiang, Shiying Zhang, Irene Shuping Zhao, Xueqi Gan, Yang Zhang   +4 more
wiley   +1 more source

Lymphatic metastasis in non‐small cell lung cancer: recent discoveries and novel therapeutic targets

, 2022
Cancer Communications, Volume 42, Issue 12, Page 1403-1406, December 2022.
Xiayao Diao, Chao Guo, Shanqing Li
wiley   +1 more source