Results 241 to 250 of about 228,627 (303)

Leptin May Promote Eosinophilic CRSwNP Progression by Enhancing Eosinophil Chemotaxis and Angiogenesis Under a Type 2 Inflammatory Milieu

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyp (CRSwNP) is a heterogeneous Type 2 inflammatory disease characterized by enhanced eosinophilic infiltration. Both innate and adaptive immunity are involved in the onset and progression of CRSwNP.
Yuki Sonoda, Yohei Sato, Yoshimasa Imoto, Mayumi Tamari, Shigeharu Fujieda   +4 more
wiley   +1 more source

Anti-Angiogenic Features of Endostatin in Obesity, Liver Fibrosis, and Hepatocellular Carcinoma. [PDF]

Biomedicines
Grewal T, Buechler C.
europepmc   +1 more source

Complementary multi‐omics profiling of chronic thromboembolic pulmonary hypertension reveals immune cell alterations, epigenetic changes, and genetically supported candidate genes

Animal Models and Experimental Medicine, EarlyView.
This study presents an integrative multi‐omics framework to uncover the molecular mechanisms and potential biomarkers of chronic thromboembolic pulmonary hypertension (CTEPH). Anthropometric and biochemical data were correlated using canonical correlation analysis, revealing key cardiometabolic associations. Single‐cell RNA sequencing identified immune
Xiaopeng Liu, Xia Zheng, Yajun Zhang, Yinghui Fang, Yanan Zhen   +4 more
wiley   +1 more source

In Vivo Target Engagement Assessment of Nintedanib in a Double-Hit Bleomycin Lung Fibrosis Rat Model. [PDF]

Int J Mol Sci
Pitozzi V, Caruso PL, Pontis S, Pioselli B, Ruscitti F, Pittelli MG, Lagrasta CAM, Quaini F, Nogara AM, Aquino G, Volta R, Faietti ML, Bonatti M, Spagnolo P, Trevisani M.   +14 more
europepmc   +1 more source

Animal models of chronic thromboembolic pulmonary hypertension

Animal Models and Experimental Medicine, EarlyView.
Current animal models of CTEPH. Created using BioRender.com. Abstract Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare, yet life‐threatening disorder characterized by persistent pulmonary vascular obstruction and elevated pulmonary artery pressure, with progressive remodeling and subsequent right heart failure.
Yong‐Jian Zhu, Lin‐Chao Zhou, Xiao‐Xue Zhang, Xiao‐Yang Ren, Yi Yan, Shao‐Fei Liu   +5 more
wiley   +1 more source

Serum Reproductive Hormone Profiles and Endometrial Expression of miR-16-5p, <i>VEGF</i> Gene, and Protein, and CD31-Positive Cells following Progesterone and EGCG Administration. [PDF]

Adv Biomed Res
Rarani FZ, Sharifi M, Rashidi B.
europepmc   +1 more source

Equine models in translational medicine: A comparative approach to human health

Animal Models and Experimental Medicine, EarlyView.
This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh, Katarzyna Ropka‐Molik   +1 more
wiley   +1 more source

Angiogenesis in ossification of the posterior longitudinal ligament: progress from mechanism to targeted intervention. [PDF]

Front Cell Dev Biol
Liu X, Wang X, Hu K, Wen H, Liu L, Li H, Che Z, Song T, Lai J, Song M, Song Y.   +10 more
europepmc   +1 more source

Growth factor applications and clinical translation: advances and challenges. [PDF]

Ann Med
Tu Y, Li B, Zheng S, Qu G, Li M, Li S, Shao C.   +6 more
europepmc   +1 more source

Dynamic regulation of receptor-modulated endothelial NADPH oxidases. [PDF]

Proc Natl Acad Sci U S A
Waldeck-Weiermair M, Das AA, Covington TA, Meitzler JL, Doroshow JH, Duan J, Fong YW, Kaynert J, Yadav S, Dutta T, Spyropoulos F, Pandey AK, Michel T.   +12 more
europepmc   +1 more source