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Role of Autotaxin in the Pathogenesis of Retina Ischemia and Its Therapeutic Implications. [PDF]
Terao R +9 more
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AdipoRon promotes angiogenesis in B-cell leukemia by modulating pro-angiogenic factors through AdipoR1. [PDF]
Mallardo M +4 more
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VEGFs, receptors and angiogenesis
Seminars in Cancer Biology, 1999Angiogenesis, the formation of new blood vessels from pre--existing ones, is central for both normal development and homeostasis as well as in certain pathological conditions. The vascular endothelial growth factors (VEGFs) and their receptors are prime regulators of both physiological and pathological angiogenesis. The different VEGFs have overlapping
T, Veikkola, K, Alitalo
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Angiogenesis, 1999
The three human VEGF receptors 1-3 mediate biological signals important for new blood vessel formation and lymphangiogenesis. Soluble VEGF receptors contain all the information necessary for high affinity ligand binding and have been used as experimental tools and regulators in several angiogenic in vitro and in vivo models.
C, Hornig, H A, Weich
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The three human VEGF receptors 1-3 mediate biological signals important for new blood vessel formation and lymphangiogenesis. Soluble VEGF receptors contain all the information necessary for high affinity ligand binding and have been used as experimental tools and regulators in several angiogenic in vitro and in vivo models.
C, Hornig, H A, Weich
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VEGF and VEGF receptors are differentially expressed in chondrocytes
Bone, 2007During long bone development, cartilage replacement by bone is governed in part by angiogenesis. Although it has been demonstrated that vascular endothelial growth factor (VEGF-A) is crucial during endochondral ossification, little is known about the involvement of the other VEGF family members.
Bluteau, G. +6 more
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The biology of VEGF and its receptors
Nature Medicine, 2003Vascular endothelial growth factor (VEGF) is a key regulator of physiological angiogenesis during embryogenesis, skeletal growth and reproductive functions. VEGF has also been implicated in pathological angiogenesis associated with tumors, intraocular neovascular disorders and other conditions.
Napoleone Ferrara, Hans-Peter Gerber
exaly +3 more sources
VEGF receptor trafficking in angiogenesis
Biochemical Society Transactions, 2009The intracellular trafficking of receptors provides a way to control the overall sensitivity of a cell to receptor stimulation. These sorting pathways are also used to shape the balance of signals that are generated in response to receptor activation.
Scott, Alice, Mellor, Harry
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Structure and function of VEGF receptors
IUBMB Life, 2009AbstractVascular endothelial growth factors (VEGFs) regulate blood and lymphatic vessel development and homeostasis. VEGFs are predominantly produced by endothelial, hematopoietic, and stromal cells in response to hypoxia and upon stimulation by growth factors such as transforming growth factor β (TGFβ), interleukins, or platelet‐derived growth factors
Stuttfeld E, Ballmer-Hofer K
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