Results 271 to 280 of about 228,627 (303)

Regulation of Angiogenesis by Controlling VEGF Receptor

Annals of the New York Academy of Sciences, 2000
Abstract: The endothelial cells cultured in collagen gel caused upregulation of KDR expression, which resulted in an increase in tube formation. Endothelial cells exposed to high glucose (33 mmol/l) for 30 days increased the tube formation induced by VEGF, but not by serum and bFGF.
S I, Murota, M, Onodera, I, Morita
openaire   +2 more sources

Biological properties of VEGF/VPF receptors

Cancer and Metastasis Reviews, 1996
B I, Terman, M, Dougher-Vermazen
exaly   +3 more sources

Human EP3I prostanoid receptor induces VEGF and VEGF receptor-1 mRNA expression

Biochemical and Biophysical Research Communications, 2008
A critical event in tumor development is the formation of new blood vessels to provide oxygen, nutrients and growth factors to the rapidly growing cancer cells. This process of angiogenesis is complex, however, it is well established that vascular endothelial growth factor (VEGF)-mediated signaling is an important early event.
Tomoko, Taniguchi, Hiromichi, Fujino, Davelene D, Israel, John W, Regan, Toshihiko, Murayama   +4 more
openaire   +2 more sources

Functions of the VEGF/VEGF Receptor System in the Vascular System

Seminars in Thrombosis and Hemostasis, 2000
The vascular endothelial growth factor (VEGF)/VEGF receptor system plays a central regulatory role in physiological and pathological angiogenesis. During embryogenesis, the VEGF/VEGF receptor system is critically involved in the formation of the vascular system by regulating both the growth and the survival of blood vessels.
openaire   +2 more sources

VEGF Receptor Signaling and Endothelial Function

IUBMB Life, 2001
AbstractAngiogenesis, the formation of new blood vessels from preexisting ones, is a central process during normal development and during pathological repair. Vascular endothelial growth factor‐A (VEGF‐A) can stimulate both physiological and pathological angiogensis.
S, Kliche, J, Waltenberger
openaire   +2 more sources

The VEGF Receptor Family

2015
The vascular endothelial growth factor (VEGF) family of ligands and receptors has been implicated in vascular development during embryogenesis. There is now a consensus that VEGF receptor signaling is also central to pathological angiogenesis associated with cancer, intraocular neovascular disorders, and other conditions.
Guanglei Zhuang, Napoleone Ferrara
openaire   +1 more source

Expression of VEGF and VEGF Receptors in Port‐Wine Stains

Otolaryngology–Head and Neck Surgery, 2008
ProblemPort‐wine stains (PWS) are vascular anomalies that may cause significant functional and psycho‐social ramifications worsening by age. Traditional management of port‐wine stains involves pulsed dye laser treatments, however only 10% of these lesions show complete response and 35% of these recur even after complete response.
Jeevan B Ramakrishnan, Chun‐Yang Fan, Neslihan Cetin, Lisa M Buckmiller, Emre A. Vural   +4 more
openaire   +1 more source

VEGF‐A, VEGF‐D, VEGF receptor‐1, VEGF receptor‐2, NF‐KB, and RAGE in atherosclerotic lesions of diabetic Watanabe heritable hyperlipidemic rabbits

The FASEB Journal, 2006
Plaque angiogenesis may be associated with the development of unstable and vulnerable plaques. Vascular endothelial growth factors (VEGFs) are potent angiogenic factors that can affect plaque neovascularization. Our objective was to determine the effect of diabetes on atherosclerosis and on the expression of angiogenesis‐related ...
Himadri Roy, Shalini Bhardwaj, Mohan Babu, Ilze Kokina, Sanna Uotila, Tiia Ahtialansaari, Teemu Laitinen, Juhana Hakumaki, Markku Laakso, Karl‐Heinz Herzig, Seppo Ylä‐Herttuala, Himadri Roy, Shalini Bhardwaj, Mohan Babu, Ilze Kokina, Sanna Uotila, Tiia Ahtialansaari, Teemu Laitinen, Juhana Hakumaki, Markku Laakso, Karl‐Heinz Herzig, Seppo Ylä‐Herttuala   +21 more
openaire   +2 more sources

VEGF and VEGF Receptor Expression after Experimental Brain Contusion in Rat

Journal of Neurotrauma, 2005
Angiogenesis following traumatic brain injury (TBI) may be of importance not only for post-traumatic reparative processes but also for the development of secondary injuries. Vascular endothelial growth factor (VEGF) is a major regulator of endothelial cell proliferation, angiogenesis, and vascular permeability, though its possible involvement in ...
Mattias K, Sköld, Christina, von Gertten, Ann-Christin, Sandberg-Nordqvist, Tiit, Mathiesen, Staffan, Holmin   +4 more
openaire   +2 more sources

VEGF and VEGF receptor levels in retinal and brain-derived endothelial cells

Biochemical and Biophysical Research Communications, 2002
Vascular endothelial cell growth factor (VEGF) is an endothelial cell-specific angiogenic and permeability-inducing factor that has been implicated in the pathogenesis of diabetic retinopathy. The objectives of this study are to compare VEGF and VEGF receptor expression between retinal and brain-derived endothelial cells cultured in 5 or 30 mM glucose ...
Talitha T, Rajah, Paula, Grammas
openaire   +2 more sources