Platelet lysate-derived neuropeptide y influences migration and angiogenesis of human adipose tissue-derived stromal cells [PDF]
, 2018 Neuropeptide Y (NPY), a powerful neurotransmitter of the central nervous system, is a key regulator of angiogenesis and biology of adipose depots. Intriguingly, its peripheral vascular and angiogenic powerful activity is strictly associated to platelets,
Bordin, Antonella +13 more
core +2 more sources
Exploring the Intracrine Functions of VEGF-A
Biomolecules, 2021 Vascular endothelial growth factor A (VEGF-A or VEGF) is a highly conserved secreted signalling protein best known for its roles in vascular development and angiogenesis.
Sophie Wiszniak, Quenten Schwarz
doaj +1 more source
Clinical Cancer Research, 2017 Purpose: Choriocarcinoma (CC) is the most malignant gestational trophoblastic disease that often develops from complete hydatidiform moles (CHM). Neither the mechanism of CC development nor its progression is yet characterized.
W. Traboulsi +17 more
semanticscholar +1 more source
Activation of protease-activated receptor 2 induces VEGF independently of HIF-1. [PDF]
PLoS ONE, 2012 BackgroundHuman adipose stem cells (hASCs) can promote angiogenesis through secretion of proangiogenic factors such as vascular endothelial growth factor (VEGF).
Jeppe Grøndahl Rasmussen +7 more
doaj +1 more source
VEGFA, B, C: Implications of the C-Terminal Sequence Variations for the Interaction with Neuropilins
Biomolecules, 2022 Vascular endothelial growth factors (VEGFs) are the key regulators of blood and lymphatic vessels’ formation and function. Each of the proteins from the homologous family VEGFA, VEGFB, VEGFC and VEGFD employs a core cysteine-knot structural domain for ...
Charles Eldrid +7 more
doaj +1 more source
Role of growth factors in the pathogenesis of tissue fibrosis in systemic sclerosis. [PDF]
, 2010 The most severe clinical and pathologic manifestations of systemic sclerosis (SSc) are the result of a fibrotic process characterized by the excessive and often progressive deposition of collagen and other connective tissue macromolecules in skin and ...
Castro, Susan V. +2 more
core +2 more sources
Tumor angiogenesis and anti-angiogenic therapy in malignant gliomas revisited [PDF]
, 2012 The cellular and molecular mechanisms of tumor angiogenesis and its prospects for anti-angiogenic cancer therapy are major issues in almost all current concepts of both cancer biology and targeted cancer therapy. Currently, (1) sprouting angiogenesis, (2)
Dumont, Daniel J. +2 more
core +1 more source
Differential expression and biochemical activity of the immune receptor Tim-3 in healthy and malignant human myeloid cells [PDF]
, 2015 The T cell immunoglobulin and mucin domain 3 (Tim-3) is a plasma membrane-associated receptor which is involved in a variety of biological responses in human immune cells.
Bardelli, Marco +4 more
core +2 more sources
Vascular endothelial growth factor directly inhibits primitive neural stem cell survival but promotes definitive neural stem cell survival [PDF]
, 2006 There are two types of neural stem cells (NSCs). Primitive NSCs [leukemia inhibitory factor (LIF) dependent but exogenous fibroblast growth factor (FGF) 2 independent] can be derived from mouse embryonic stem (ES) cells in vitro and from embryonic day 5 ...
Chaddah, R +7 more
core +3 more sources
Functional VEGF and VEGF receptors are expressed in human medulloblastomas [PDF]
Neuro-Oncology, 2007 Vascular endothelial growth factor (VEGF) is one of the key regulators of tumor neoangiogenesis. It acts through two types of high-affinity tyrosine kinase receptors (VEGF receptor-1 [VEGFR-1]/fms-related tyrosine kinase 1 [Flt-1] and VEGFR-2/kinase domain receptor [KDR]) expressed on endothelial cells.
SLONGO, MARA LILIANA +8 more
openaire +3 more sources