Results 31 to 40 of about 2,633,569 (375)
Clinical Cancer Research, 2017 Purpose: Choriocarcinoma (CC) is the most malignant gestational trophoblastic disease that often develops from complete hydatidiform moles (CHM). Neither the mechanism of CC development nor its progression is yet characterized.
W. Traboulsi +17 more
semanticscholar +1 more source
Vascular endothelial growth factor directly inhibits primitive neural stem cell survival but promotes definitive neural stem cell survival [PDF]
, 2006 There are two types of neural stem cells (NSCs). Primitive NSCs [leukemia inhibitory factor (LIF) dependent but exogenous fibroblast growth factor (FGF) 2 independent] can be derived from mouse embryonic stem (ES) cells in vitro and from embryonic day 5 ...
Chaddah, R +7 more
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Activation of protease-activated receptor 2 induces VEGF independently of HIF-1. [PDF]
PLoS ONE, 2012 BackgroundHuman adipose stem cells (hASCs) can promote angiogenesis through secretion of proangiogenic factors such as vascular endothelial growth factor (VEGF).
Jeppe Grøndahl Rasmussen +7 more
doaj +1 more source
VEGFA, B, C: Implications of the C-Terminal Sequence Variations for the Interaction with Neuropilins
Biomolecules, 2022 Vascular endothelial growth factors (VEGFs) are the key regulators of blood and lymphatic vessels’ formation and function. Each of the proteins from the homologous family VEGFA, VEGFB, VEGFC and VEGFD employs a core cysteine-knot structural domain for ...
Charles Eldrid +7 more
doaj +1 more source
A multiscale hybrid model for pro-angiogenic calcium signals in a vascular endothelial cell [PDF]
, 2012 Cytosolic calcium machinery is one of the principal signaling mechanisms by which endothelial cells (ECs) respond to external stimuli during several biological processes, including vascular progression in both physiological and pathological conditions ...
A. Balter +102 more
core +1 more source
VEGF receptor signaling in vertebrate development [PDF]
Organogenesis, 2008 The secreted glycoprotein vascular endothelial growth factor A (VEGF or VEGFA) affects many different cell types and modifies a wide spectrum of cellular behaviors in tissue culture models, including proliferation, migration, differentiation and survival.
Vieira, J., Ruhrberg, C., Schwarz, Q.
openaire +4 more sources
Tumor angiogenesis and anti-angiogenic therapy in malignant gliomas revisited [PDF]
, 2012 The cellular and molecular mechanisms of tumor angiogenesis and its prospects for anti-angiogenic cancer therapy are major issues in almost all current concepts of both cancer biology and targeted cancer therapy. Currently, (1) sprouting angiogenesis, (2)
Dumont, Daniel J. +2 more
core +1 more source
The Role of VEGF and VEGF Receptors in Carcinogenesis [PDF]
Journal of Carcinogenesis & Mutagenesis, 2012 The vascular endothelial growth factor (VEGF) family and its associated cognate receptors are critical components of angiogenesis, the process of new blood vessel formation. Under normal conditions, angiogenesis supports organism development and tissue homeostasis in a tightly controlled fashion.
openaire +1 more source
Respiratory Research, 2018 Dysregulation of VEGF-A bioavailability has been implicated in the development of lung injury/fibrosis, exemplified by Idiopathic Pulmonary Fibrosis (IPF). VEGF-A is a target of the hypoxic response via its translational regulation by HIF-1α. The role of
Shaney L. Barratt +6 more
doaj +1 more source
VEGF189 binds NRP1 and is sufficient for VEGF/NRP1-dependent neuronal patterning in the developing brain [PDF]
, 2015 © 2015. Published by The Company of Biologists Ltd. This research was funded by a Wellcome Trust PhD fellowship to M.T. [092839/Z/10/Z] and a BBSRC project grant to C.R. and L.E. [BB/J00930X/1].
Cariboni, Anna +6 more
core +2 more sources