Results 91 to 100 of about 1,315,367 (316)

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Heavy vehicle pitch dynamics and suspension tuning [PDF]

open access: yes, 2008
The influence of suspension tuning of passenger cars on bounce and pitch ride performance has been explored in a number of studies, while only minimal efforts have been made for establishing similar rules for heavy vehicles.
Cao, Dongpu   +2 more
core  

Development of a simplified human body dynamics model for motion control on a vehicle

open access: yesMechanical Engineering Journal, 2016
This study aims to create a system that can be used to evaluate vehicle characteristics while simultaneously controlling human body behavior through numerical simulations.
Shoichiro TAKEHARA   +4 more
doaj   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird   +9 more
wiley   +1 more source

A Multi-Feature LED Bit Detection Algorithm in Vehicular Optical Camera Communication

open access: yesIEEE Access, 2019
In a vehicular optical camera communication (VOCC) system, digital information is transmitted using LED panels and received using cameras. The transmitted bits are obtained by processing the captured images to detect the ON and OFF statuses of LEDs in ...
Trong-Hop Do, Myungsik Yoo
doaj   +1 more source

A Q‐Learning Algorithm to Solve the Two‐Player Zero‐Sum Game Problem for Nonlinear Systems

open access: yesInternational Journal of Adaptive Control and Signal Processing, Volume 39, Issue 3, Page 566-581, March 2025.
A Q‐learning algorithm to solve the two‐player zero‐sum game problem for nonlinear systems. ABSTRACT This paper deals with the two‐player zero‐sum game problem, which is a bounded L2$$ {L}_2 $$‐gain robust control problem. Finding an analytical solution to the complex Hamilton‐Jacobi‐Issacs (HJI) equation is a challenging task.
Afreen Islam   +2 more
wiley   +1 more source

The Vehicle Detector Clearinghouse (VDC) : a summary report [PDF]

open access: yes
The mission of the VDC is to provide information to transportation agencies on the capabilities of commercially available vehicle detectors by gathering, organizing, and sharing information concerning tests and test procedures in a timely, efficient, and
Vehicle Detector Clearinghouse (Southwest Technology Development Institute)
core  

Intelligent mobility control of a hybrid electric off-road vehicle with individual wheel control [PDF]

open access: yes, 2003
This work focuses on the potential benefits that can be gained from the use of Individual Wheel Control on a large off-road vehicle. The vehicle concerned is a theoretical, six-wheel drive, off-road Hybrid-Electric Vehicle based on an existing ...
Jackson, Andrew Edward
core  

Air‐Pressure–Actuated Vibroacoustic Metamaterial With Tunable Bandgap: Design, Modeling, and Characterization

open access: yesAdvanced Engineering Materials, EarlyView.
This article presents the design, modeling, and characterization of air‐pressure–actuated programmable vibroacoustic metamaterials (PVAMM). The study focuses on leveraging air pressure to dynamically tune resonance frequencies for effective noise attenuation.
William Kaal   +2 more
wiley   +1 more source

Correlation of subjective and objective handling of vehicle behaviour [PDF]

open access: yes, 2002
This thesis presents the results of a research project which sought to find links between driver subjective ratings and objective measures of vehicle handling.
Ash, Howard Alan Simon
core  

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