Results 71 to 80 of about 3,575,601 (344)
, 2019 The majority of current studies on autonomous vehicle control via deep reinforcement learning (DRL) utilize point-mass kinematic models, neglecting vehicle dynamics which includes acceleration delay and acceleration command dynamics.
Azad, Nasser L., Lin, Yuan, McPhee, John
core +1 more source
A predefined channel coefficients library for vehicle-to-vehicle communications [PDF]
, 2015 It is noticeable that most of VANETs communications tests are assessed through simulation. In a majority of simulation results, the physical layer is often affected by an apparent lack of realism.
Al-Khalil, Ahmad Baheej +2 more
core +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Earth-to-orbit transportation for solar power satellites [PDF]
, 1980 The cargo transport capability and the cost of space transportation operations for transportation of solar power satellites (SPS) to space are addressed. The history of SPS launch vehicle evolution is shown. Alternative vehicle designs developed include:
Hanley, G., Woodcock, G. R.
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ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
RESULTS OF STUDYING ROAD CONSTRUCTION PARAMETERS' CONDITION
Architecture and Engineering, 2018 A system for the accounting of road infrastructure facilities' parameters specified during design and construction of motor roads. A study of parameters' condition was performed.
Elena Kurakina, Elena Kurakina
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
A damper for ground wind-induced launch vehicle oscillations [PDF]
, 1975 Prelaunch oscillatory bending deflections of the Atlas/Centaur launch vehicle are restrained by a damper mechanism mounted on the end of a horizontal boom supported from the umbilical tower. A single vertical pin on the vehicle engages the mechanism, and
Bodle, J. G., Hackley, D. S.
core +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
THE CHOICE OF A RATIONAL STRUCTURAL DESIGN OF ELECTRODYNAMIC TRANSPORT SYSTEMS
Nauka ta progres transportu, 2009 The design schemes of electrodynamic maglev systems with a plane track structure are developed and the results of investigation of levitating motion of such systems along rectilinear or curvilinear tracks are presented.
M. O. Radchenko +3 more
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