Results 231 to 240 of about 127,844 (312)
β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma
Advanced Science, EarlyView.β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto +20 more
wiley +1 more source
The Lateral Control of Unmanned Vehicles Based on Neural Network Identification and a Fast Tube Model Predictive Control Algorithm. [PDF]
Sensors (Basel)Dai Y, Zhou Z.
europepmc +1 more source
Advanced Science, EarlyView.Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng +8 more
wiley +1 more source
A hierarchical lateral stability control strategy of distributed drive electric vehicles based on extended Kalman filter and integral terminal sliding mode control. [PDF]
PLoS OneWang J, Zhao Y, Gao W, Deng Z.
europepmc +1 more source
Advanced Science, EarlyView.ABSTRACT Diabetes mellitus‐induced erectile dysfunction (DMED) is a highly prevalent complication among diabetic patients; however, its underlying pathogenic mechanisms remain incompletely understood. Metabolic disorder is a hallmark of diabetes, yet its precise contribution to DMED progression is not well defined.
Wanyang Guo +14 more
wiley +1 more source
From Light Pulses to Selective Enhancement: Performance Analysis of Event-Based Object Detection Under Pulsed Automotive Headlight Illumination. [PDF]
Sensors (Basel)Haensel L, Bertram T.
europepmc +1 more source
Advanced Science, EarlyView.Prolonged exposure to stiff extracellular matrix drives cancer‐associated fibroblasts into a persistently activated myofibroblast state. Two parallel pathways are identified: β1 integrin activation smoothens the nuclear lamina to reduce lamin–chromatin contacts, while the formin mDia2 regulates nuclear actin to alter chromatin organization.
Swathi Packirisamy +4 more
wiley +1 more source
Learning-aided observer design for improving autonomous vehicle safety. [PDF]
Sci RepMihály A +4 more
europepmc +1 more source
Advanced Science, EarlyView.The pholidota‐inspired electronic skin is successfully constructed, originally realized four‐state reversible switching of terahertz‐wave reflection, absorption, transmission, and secondary reflection. In response to external demands, it issues deformation instructions, verifies the deformation state after the equipment executes the action, and thus ...
Shangjing Li +4 more
wiley +1 more source
Impact assessment of the transported load mass on the lateral dynamics of a light delivery vehicles. [PDF]
Sci RepJagelčák J +3 more
europepmc +1 more source