Results 31 to 40 of about 81,148 (267)
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
A Review of Active Aerodynamic Systems for Road Vehicles
Comfort, safety, high travel speeds, and low fuel consumption are expected characteristics of modern cars. Some of these are in conflict with one other. A solution to this conflict may be time-varying body geometry realized by moving aerodynamic elements
Janusz Piechna
doaj +1 more source
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Research on Yaw Moment Control System for Race Cars Using Drive and Brake Torques
The yaw acceleration required for circuit driving is determined by the time variation of the yaw rate due to two factors: corner radius and velocity at the center of gravity. Torque vectoring systems have the advantage where the yaw moment can be changed
Ikkei Kobayashi +9 more
doaj +1 more source
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Performance comparisons of piezoelectric energy harvesters under different stochastic noises
Harvesting energy utilizing the electromechanical coupling mechanism of piezoelectric materials in a noise environment has become important for developing applicable micropower generators.
Sha Zhou, Tianjun Yu
doaj +1 more source
Survey of the Application Fields and Modeling Methods of Automotive Vehicle Dynamics Models
In this paper, a review is presented on automotive vehicle dynamics modeling. Applied vehicle dynamics models from various application fields are analyzed and classified in the first section.
András Szántó +2 more
doaj +1 more source

