Results 51 to 60 of about 437,592 (262)

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Vehicle kilometers of travel and fuel consumption rate for estimating CO2 emission of vehicles in Khon Kaen city

open access: yesKKU Engineering Journal, 2014
The Vehicle Kilometers of Travel (VKT) of each vehicle type can be applied to estimate amount of fuel consumption and CO2 emission from transport sector of nation. The objectives of this study are to survey and develop VKT model, fuel consumption rate of
Thaned Satiennam   +4 more
doaj  

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Road Transport Vehicles for Hauling Uncomminuted Forest Energy Products in Sweden

open access: yesInternational Journal of Forestry Research, 2013
Forestry residues as a renewable energy source are becoming increasingly competitive to fossil fuels. An important issue, however, is effective transportation solutions for this type of material. In this paper we describe and discuss several alternative
Reza Mortazavi, Jerry Johansson
doaj   +1 more source

The influence of vehicle type composition on heterogeneous traffic flow [PDF]

open access: yesEPJ Web of Conferences
To better understand heterogeneous trafic with weak lane discipline (2D mixed trafic), it is essential to investigate the effects of vehicle type composition (e.g., motorcycles, cars) on trafic characteristics.
Asai Nichika   +4 more
doaj   +1 more source

Vehicle Type Detection by Convolutional Neural Networks [PDF]

open access: yes, 2017
Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech.
Miguel A. Molina-Cabello   +3 more
openaire   +2 more sources

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

open access: yesFEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

The State of Electric Vehicle Adoption in Colorado for Multifamily versus Single-Family Dwellings: A Methodology for Quantifying Deviation from Parity

open access: yesFindings
Given that electric vehicle adoption is well underway, the spatial distribution of electric vehicle owners by housing type---single-family or multifamily--- shows whether parity (equal adoption rates) is being achieved or to what extent adoption by ...
Luna Hoopes, Alana Wilson
doaj   +1 more source

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