Results 51 to 60 of about 23,681,723 (385)
The feasibility of a road vehicle mounted aerodynamic testing apparatus [PDF]
A ground vehicle mounted aerodynamic testing apparatus has been identified as a candidate concept for a low-cost alternative to traditional techniques.
Adams, Jordan
core +1 more source
Electric Vehicle and its Types
Electric vehicles are an important option for reducing greenhouse gas emissions. Electric vehicles not only reduce dependence on fossil fuels, but also reduce the impact of ozone-depleting substances and promote widespread adoption of renewable energies.
openaire +1 more source
Computer simulation of a series and parallel hybrid electric vehicle [PDF]
Although the internal combustion engine (ICE) vehicle is the most popular vehicle type in the world it has serious problems relating to its exhaust emissions and the limitation of petroleum resource.
Lee, Wonhee
core
The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Modelling the vehicle in vehicle-infrastructure dynamic interaction studies [PDF]
This paper presents the equations of motion for a general articulated road vehicle, with variable numbers of wheels for the tractor and trailer. The equations are applicable to vehicle-bridge dynamic interaction problems for two and three dimensional ...
O\u27Brien, Eugene J. +3 more
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
This study investigated several factors that may influence driver actions throughout the yellow interval at urban signalised intersections. The selected samples include 2,168 observations.
Ahmad H. Alomari +4 more
doaj +1 more source
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source

