Results 71 to 80 of about 23,681,723 (385)

Access to Data in Connected Cars and the Recent Reform of the Motor Vehicle Type Approval Regulation

Social Science Research Network, 2019
The need for regulatory solutions for access to in-vehicle data and resources of connected cars is one of the big controversial and unsolved policy issues. Last year the EU revised the Motor Vehicle Type Approval Regulation which already entailed a FRAND-
Wolfgang Kerber, D. Moeller
semanticscholar   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

A Vehicle Type Dependent Car-following Model Based on Naturalistic Driving Study

Electronics, 2019
In this paper, a car-following model considering the preceding vehicle type is proposed to describe the longitudinal driving behavior closer to reality.
P. Wu, Feng Gao, Ke-Qiang Li
semanticscholar   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Suspension parameter design of underframe equipment considering series stiffness of shock absorber

Advances in Mechanical Engineering, 2020
In this article, a vertical rigid–flexible coupling model between the vehicle and the equipment is established. Considering the series stiffness of hydraulic shock absorbers, the underframe equipment is like a three-element-type Maxwell model dynamic ...
Jie Chen, Yangjun Wu, Xiaolong He, Limin Zhang, Shijie Dong   +4 more
doaj   +1 more source

Impacts of speed variations on freeway crashes by severity and vehicle type.

Accident Analysis and Prevention, 2018
Speed variations are identified as potentially important predictors of freeway crash rates; however, their impacts on crashes are not entirely known.
Pushpa Choudhary, Marianna Imprialou, N. Velaga, A. Choudhary   +3 more
semanticscholar   +1 more source

Final report

, 2010
Title from cover.; Earlier ed. issued as: Preliminary report / State of Connecticut, Electric Vehicle Infrastructure Council ; by Kevin M. DelGobbo, Joan McDonald.
Connecticut. Electric Vehicle Infrastructure Council.
core   +1 more source

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

Molecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna, Jodie Hay, Michael W. Moles, Lucy Clarke, Jennifer Cassels, Alison Sefcick, Alison M. McCaig, Heather G. Jørgensen, Alison M. Michie   +8 more
wiley   +1 more source

Motor Vehicle Usage Patterns in Australia: A Comparative Analysis of Driver, Vehicle & Purpose Characteristics for Household & Freight Travel [PDF]

An ordered probit model is used to predict motor vehicle usage in Australia on the basis of the unit record files underlying the Australian Bureau of Statistics’ Survey of Motor Vehicle Use. Both household and freight transport are analysed.
Andrew Worthington, Kathleen Goffey
core  

Overcoming platinum resistance by the disulfiram metabolite CuET in novel preclinical models of human carcinomas

Molecular Oncology, EarlyView.
Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis, Tereza Buchtová, Jirina Bartkova, Marie Lund Bay, Christoffer Lynge Halvorsen, Zuzana Machacova, Zdenek Skrott, Martin Mistrik, Ekaterina Dulina, Miguel Andujar‐Sanchez, Estrid Høgdall, Tine Henrichsen Schnack, Claus Høgdall, Berit Jul Mosgaard, Marie Boennelycke, Jacob Brink Laursen, Allan Jensen, Susanne K. Kjær, Tuula Kallunki, Robert Strauss, Jiri Bartek   +20 more
wiley   +1 more source