Results 21 to 30 of about 282,137 (268)
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Chengshi guidao jiaotong yanjiuObjectiveAIBs (axlebox-integrated bogies) feature high equipment space utilization and superior performance. To match such bogies and meet the lightweight development requirements of urban rail transit vehicles, it is necessary to design a novel traction-
Zhanyu XIE +5 more
doaj +1 more source
SSRN Electronic Journal, 2008 Historically, the world economy has been dominated by a single currency accepted in the exchange of goods and assets among countries. In recent decades, the U.S. dollar has played this role. The dollar acts as a “vehicle currency” in the sense that agents in nondollar economies will generally engage in currency trade indirectly using the U.S.
Devereux, Michael B., Shi, Shouyong
openaire +2 more sources
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Wheel Load Calculation Methods for Articulated Suburban Railway Trains
Chengshi guidao jiaotong yanjiuObjective The distribution of wheel loads and axle loads plays a critical role in train operational safety and structural reliability, and the accuracy of wheel load calculation is an important prerequisite for the vehicle's top-level design.
Feng QIANG +5 more
doaj +1 more source
Chengshi guidao jiaotong yanjiu［Objective］ The OD (obstacle deflector) serves as a primary passive safety device on high-speed trains, effectively clearing obstacles between the wheels and the tracks.
LI Hongshuang +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Dry-fog disinfection as a method for processing vehicles for passenger transport
Current Directions in Biomedical Engineering, 2022 Due to the corona pandemic, the demand for efficient and fast-acting disinfection measures is high. In this work, the disinfecting potential of a dry fogging technology (Apollon Biotech GmbH, Germany) was investigated for the possibility of disinfection ...
Buhl Sebastian +2 more
doaj +1 more source
Impact of Climate Change on the Energy Consumption of Passenger Car Vehicles
World Electric Vehicle Journal, 2022 The energy consumption of passenger vehicles is affected by the physical properties of the environment. The ambient temperature in particular has a significant impact on the operating energy consumption.
Samuel Hasselwander +2 more
doaj +1 more source