Results 31 to 40 of about 720,508 (305)
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
, 2012 Report submitted by the Texas Department of Motor Vehicles containing background information on the department, and summaries of requests for appropriations and expenditures for the fiscal years 2014 and 2015 with supporting ...
Texas. Department of Motor Vehicles.
core +1 more source
Dry-fog disinfection as a method for processing vehicles for passenger transport
Current Directions in Biomedical Engineering, 2022 Due to the corona pandemic, the demand for efficient and fast-acting disinfection measures is high. In this work, the disinfecting potential of a dry fogging technology (Apollon Biotech GmbH, Germany) was investigated for the possibility of disinfection ...
Buhl Sebastian +2 more
doaj +1 more source
Impact of Climate Change on the Energy Consumption of Passenger Car Vehicles
World Electric Vehicle Journal, 2022 The energy consumption of passenger vehicles is affected by the physical properties of the environment. The ambient temperature in particular has a significant impact on the operating energy consumption.
Samuel Hasselwander +2 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Integrated Vehicle Scheduling and Vehicle Assignment [PDF]
Acta Cybernetica, 2018 The vehicle scheduling problem has been extensively studied in the past decades. Yet, most models and methods given in the literature consider only a theoretical scenario where vehicles just have to service the timetabled trips of the input. However, schedules created this way cannot be used in real life, as they should also consider constraints such ...
József Békési +2 more
openaire +3 more sources
Bureau of Motor Vehicles facts and figures
Annual; Electronic coverage as of Jan. 22, 2010: 2006-; Title from caption (viewed Mar.
core +3 more sources
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Design Method of Carbody Front-end Energy-absorption Device for High-speed Trains
Chengshi guidao jiaotong yanjiuObjectiveTo optimize the passive safety protection performance of high-speed trains, it is necessary to design a carbody front-end energy-absorption device suitable for high-speed trains, so as to reduce the carbody deformation during collisions and ...
Shihong JIANG +4 more
doaj +1 more source