Results 51 to 60 of about 9,831 (263)

Danger Aware Vehicular Networking

CoRR, 2020
IEEE 802.11p is one of the key technologies that enable Dedicated Short-Range Communications (DSRC) in intelligent transportation system (ITS) for safety on the road. The main challenge in vehicular communication is the large amount of data to be processed. As vehicle density and velocity increases, the data to be transmitted also increases.
Dessalgn, Tsigigenet, Kim, Seungmo
openaire   +2 more sources

A Distributed Cooperative Localization Strategy in Vehicular-to-Vehicular Networks [PDF]

Sensors, 2020
This work develops a distributed message-passing approach to cooperative localization for autonomous mobile vehicles that communicate via mm-wave wireless connection in vehicle-to-vehicle networks. Vehicles in the network obtain the measurement information about the relative distance and the angle of arrival from the mm-wave connections made with each ...
Minji Kim 0006, Hong Ki Kim, Sang Hyun Lee   +2 more
openaire   +3 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Software-Defined Approach for Communication in Autonomous Transportation Systems

EAI Endorsed Transactions on Energy Web, 2017
Autonomous driving technology offers a promising solution to reduce road accidents, traffic congestion, and fuel consumption. The management of vehicular networks is challenging as it demands mobility, location awareness, high reliability and low latency
Piyush Dhawankar, Mohsin Raza, Hoa Le-Minh, Nauman Aslam   +3 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Blockchain enabled task offloading based on edge cooperation in the digital twin vehicular edge network

Journal of Cloud Computing: Advances, Systems and Applications, 2023
The rapid development of the Internet of Vehicles (IoV) along with the emergence of intelligent applications have put forward higher requirements for massive task offloading. Even though Mobile Edge Computing (MEC) can diminish network transmission delay
Chunhai Li, Qiyong Chen, Mingfeng Chen, Zhaoyu Su, Yong Ding, Dapeng Lan, Amir Taherkordi   +6 more
doaj   +1 more source

Pulse Synchronization for Vehicular Networks [PDF]

2018 IEEE Intelligent Vehicles Symposium (IV), 2018
This paper improves pulse-coupled synchronization for highly dynamic wireless networks, where vehicles may move unpredictably, causing topological changes of the network. For pulse-coupled methods, vehicles broadcast zero-bit pulses to estimate the clock differences to their neighbors.
Cheng-Yu Han, Thomas Nowak, Alain Lambert   +2 more
openaire   +2 more sources

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source