Results 41 to 50 of about 3,033,628 (267)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Randomized, Open-Label Phase 3 Study Evaluating Immunogenicity, Safety, and Reactogenicity of RSVPreF3 OA Coadministered with FLU-QIV-HD in Adults Aged ≥ 65

Infectious Diseases and Therapy
Introduction Respiratory syncytial virus (RSV) and influenza pose major disease burdens in older adults due to an aging immune system and comorbidities; seasonal overlap exists between these infections.
Robert Buynak, Kevin Cannon, David DeAtkine, John Kirby, Lisa Usdan, Amit Bhavsar, Catherine Gérard, Anastasia Kuznetsova, Amulya Jayadev, Hiwot Amare, Sofia Valenciano, Nadia Meyer   +11 more
doaj   +1 more source

Hydrodynamics of an in-pond raceway system with an aeration plug-flow device for application in aquaculture: an experimental study [PDF]

Royal Society Open Science, 2019
An in-pond raceway system (IPRS) is an effective intensive aquaculture practice for regions with high water consumption and limited land resources. Water flow and dissolved oxygen (DO) are important for sustainable aquaculture.
Wuhua Li, Xiangju Cheng, Jun Xie, Zhaoli Wang, Deguang Yu   +4 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Video-Biomechanical Analysis of the Shoulder Kinematics of Impact from Sode-Tsurikomi-Goshi and Tsurikomi-Goshi Judo Throws in Elite Adult Judoka

Applied Sciences
Background: The aim of this study was to calculate and compare the peak acceleration and peak negative velocity of uke’s shoulder during the course of two judo throwing techniques, Sode-Tsurikomi-Goshi (STG) and Tsurikomi-Goshi (TG).
Maria Pantelidou, Wiesław Błach, Łukasz Rydzik, Tadeusz Ambroży, Ruqayya Lockhart, Manuela Angioi, Krzysztof Sokołowski, Nikos Malliaropoulos   +7 more
doaj   +1 more source

A Simplified Computational Model for the Location of Depth Average Velocity in a Rectangular Irrigation Channel

Applied Sciences, 2019
Flow measurements in open channels have often utilized velocity-area methods. Thus, estimations of the average velocity in a cross-section of rural canals play an important role in the flow measurement of an irrigation district.
Zhuangzhuang Ma, Zhangsheng Wu, Tongshu Li, Yu Han, Jian Chen, Liangpei Zhang   +5 more
doaj   +1 more source

Protostellar Jets Enclosed by Low-velocity Outflows

, 2014
A protostellar jet and outflow are calculated for \sim 270 yr following the protostar formation using a three dimensional magnetohydrodynamics simulation, in which both the protostar and its parent cloud are spatially resolved. A high-velocity (\sim100km/
Machida, Masahiro N.
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

The Relationship Between the Upper-Body Strength Characteristics with Velocity and Power Parameters During the Bench Throw Movement: Is Sport Branch An Inportant Factor ?

Türk Spor ve Egzersiz Dergisi, 2020
The purpose of this study was to investigate whether the relationship between the upper-body strength characteristic with velocity and power parameters during the bench throw exercise shows a significant difference according to sports branches.
Serdar Bayrakdaroğlu, İbrahim Can
doaj  

Investigation of exit-velocity stratification effects on jets in a crossflow (STRJET) [PDF]

, 1974
Program determines flow field about jets with velocity stratification exhausting into crossflow. Jets with three different types of exit-velocity stratification have been considered: (a) jets with relatively high-velocity core, (b) jets with relatively ...
Ziegler, H.
core   +1 more source