Results 51 to 60 of about 108,996 (213)
Velocity Centroids as Tracers of the Turbulent Velocity Statistics [PDF]
The Astrophysical Journal, 2005 We use the results of magnetohydrodynamic (MHD) simulations to emulate spectroscopic observations and use maps of centroids to study their statistics. In order to assess under which circumstances the scaling properties of the velocity field can be retrieved from velocity centroids, we compare two point statistics (structure functions and power-spectra)
Esquivel, A., Lazarian, A.
openaire +2 more sources
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Velocity, 2021 Metode penelitian yang digunakan adalah deskriptif kuantitatif. Data yang digunakan yaitu data sekunder. Pengumpulan data dengan metode dokumentasi yaitu mengumpulkan laporan keuangan BPRS Al-Makmur tahun 2016-2020.
Yimmi Syavardie, Yenty Astarie Dewi
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
VelocityPerkembangan industri perbankan menuntut setiap bank untuk menjaga tingkat kesehatan keuangan dan operasionalnya guna mempertahankan kepercayaan nasabah dan stabilitas sistem keuangan.
Riska Tri Oktaviani +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
VelocityPeningkatan volatilitas ketidakpastian ekonomi global dapat menimbulkan efek spillover pada perekonomian domestik, termasuk perbankan syariah. Penelitian ini mengkaji dampak Global Economic Policy Uncertainty (GEPU) terhadap pembiayaan bank umum syariah ...
Mashilal, Arif Afendi
doaj +1 more source