Results 71 to 80 of about 2,427,814 (269)

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

A simple method for measuring power, force, velocity properties, and mechanical effectiveness in sprint running

open access: yesScandinavian Journal of Medicine & Science in Sports, 2016
This study aimed to validate a simple field method for determining force– and power–velocity relationships and mechanical effectiveness of force application during sprint running.
P. Samozino   +6 more
semanticscholar   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Pemetaan Penelitian Pembiayaan di Baitul Mal wat Tamwil: Studi Bibliometrik VOSviewer dan Literature Review

open access: yesVelocity
This study aims to map the development of studies on financing in Baitul Mal Wat Tamwil through a bibliometric approach with the help of a VOSviewer and a literature review.
Fahmi Amru Ar-Rifa'i Fahmi   +3 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Analisis Efektivitas Pengelolaan dan Pendistribusian Zakat dalam Mengurangi Kemiskinan Melalui Program Pemberdayaan Ekonomi pada BAZNAS Kota Batu : Pendekatan Kuantitatif

open access: yesVelocity
The problem of poverty in the city of Batu is still exist which motivated by several factors due to the low provision of zakat, infaq and alms funds collected from the community through BAZNAS Batu City.
Nur Afifa Aulia   +3 more
doaj   +1 more source

Changes in the Velocity Structure of the Greenland Ice Sheet

open access: yesScience, 2006
Using satellite radar interferometry observations of Greenland, we detected widespread glacier acceleration below 66° north between 1996 and 2000, which rapidly expanded to 70° north in 2005.
E. Rignot, P. Kanagaratnam
semanticscholar   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

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