Results 81 to 90 of about 2,427,814 (269)

Peranan Kualitas Layanan pada Aplikasi PLN Mobile dan Harga terhadap Kepuasan Pelanggan di PT. PLN (Persero) UP3 Palembang ULP Rivai

Velocity
Penelitian ini bertujuan untuk mengukur pengaruh kualitas layanan melalui aplikasi PLN Mobile terhadap kepuasan pelanggan di PT. PLN (Persero) UP3 Palembang ULP Rivai.
Robetam Simanjuntak, Sulaiman Helmi, Trisninawati, Muji Gunarto   +3 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Service Quality dan Digital Banking meningkatkan Loyalitas Nasabah Bank Syariah Indonesia? Kepuasan sebagai Variabel Intervening: Nasabah BSI Civitas Akademika FEBI UIN K.H. Abdurrahman Wahid Pekalongan

Velocity
Bank Syariah Indonesia tak lepas dari nasabah yang menjadi peran penting dalam menjalankan kegiatan operasionalnya. Terdapat beberapa faktor yang menjadi pengukur kepuasan nasabah. Hal ini menjadi penting untuk diketahui agar loyalitas nasabah yang telah
Hany Lutfi
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Meningkatkan Kepuasan Nasabah dengan Kualitas Pelayanan, Citra Perusahaan dan Kepercayaan pada Bank Jateng Syariah Cabang Pekalongan

Velocity
Penelitian ini bertujuan untuk mengukur kepuasan nasabah dalam menabung. beberapa variabel digunakan diantaranya Kualitas pelayanan sebagai landasan utama untuk mengetahui tingkat kepuasan konsumen, citra perusahaan merupakan salah satu aset terpenting ...
Tamamudin, Desy Prastyani
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

THE RADIAL VELOCITY EXPERIMENT (RAVE): FIFTH DATA RELEASE [PDF]

, 2013
Data Release 5 (DR5) of the Radial Velocity Experiment (RAVE) is the fifth data release from a magnitude-limited ( ) survey of stars randomly selected in the Southern Hemisphere. The RAVE medium-resolution spectra ( ) covering the Ca-triplet region (8410–
M. Steinmetz, T. Zwitter, A. Siebert, F. Watson, K. Freeman, U. Munari, R. Campbell, M. Williams, G. Seabroke, R. Wyse, Q. Parker, O. Bienaymé, S. Roeser, B. Gibson, G. Gilmore, E. Grebel, A. Helmi, J. Navarro, D. Burton, C. Cass, J. Dawe, K. Fiegert, M. Hartley, K. Russell, W. Saunders, H. Enke, J. Bailin, J. Binney, J. Bland-Hawthorn, C. Boeche, W. Dehnen, D. Eisenstein, N. Evans, M. Fiorucci, J. Fulbright, O. Gerhard, U. Jauregi, A. Kelz, L. Mijović, I. Minchev, G. Parmentier, J. Peñarrubia, A. Quillen, M. Read, G. Ruchti, R. Scholz, A. Siviero, M. Smith, R. Sordo, L. Veltz, S. Vidrih, R. V. Berlepsch, B. Boyle, E. Schilbach   +53 more
semanticscholar   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source