Results 81 to 90 of about 3,033,628 (267)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Collision of One-Dimensional Nonlinear Chains

open access: yes, 2002
We investigate one-dimensional collisions of unharmonic chains and a rigid wall. We find that the coefficient of restitution (COR) is strongly dependent on the velocity of colliding chains and has a minimum value at a certain velocity.
A.G. Basile   +13 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Unusual optical coherence tomography and fundus autofluorescence findings of eclipse retinopathy

open access: yesIndian Journal of Ophthalmology, 2012
A 63-year-old female patient complained of dimness in the central field of vision in the left eye after viewing an annular partial eclipse without adequate eye protection on 22 July 2009. Fundoscopy showed a wrinkled macular surface.
Kun-Hsien Li   +3 more
doaj   +1 more source

Adiabatic sound velocity and compressibility of a trapped d-dimensional ideal anyon gas

open access: yes, 2012
The adiabatic sound velocity and compressibility for harmonically trapped ideal anyons in arbitrary dimensions are calculated within Haldane fractional exclusion statistics.
Anghel   +36 more
core   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Velocity accelerator for particles [PDF]

open access: yes, 1972
Sheet explosive and metal tube, fitted to the inner periphery of a cam-shaped chamber, accelerate particles to velocities nearing 20 km/sec to evaluate efficacy of spacecraft meteoroid ...
Wilson, A. H.
core   +1 more source

Dissipative flow and vortex shedding in the Painlev\'e boundary layer of a Bose Einstein condensate

open access: yes, 2003
Raman et al. have found experimental evidence for a critical velocity under which there is no dissipation when a detuned laser beam is moved in a Bose-Einstein condensate. We analyze the origin of this critical velocity in the low density region close to
A. Sommerfeld   +5 more
core   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Gait Speed as a Screening Tool for Foot Pain and the Risk of Falls in Community-Dwelling Older Women: A Cross-Sectional Study

open access: yesClinical Interventions in Aging, 2020
Lovro Štefan,1 Mario Kasović,1,2 Martin Zvonar2,3 1Faculty of Kinesiology, Department of General and Applied Kinesiology, University of Zagreb, Zagreb, Croatia; 2Faculty of Sports Studies, Department of Sports Motorics, Masaryk University, Brno ...
Štefan L, Kasović M, Zvonar M
doaj  

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