Results 61 to 70 of about 291,671 (267)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Surface Air Movement: An Important Contributor to Ventilation of Isolated Subsurface Structures?
Infrastructures, 2019 This study reports on near-surface airspeed measured using a fast-responding thermoanemometer during an investigation of ventilation of an isolated subsurface structure induced by natural forces. Air speed changes continuously, rapidly, and unpredictably
Thomas Neil McManus, Assed Haddad
doaj +1 more source
Single-Point Velocity Distribution in Turbulence [PDF]
Physical Review Letters, 1997 9 pages, revtex, no ...
Falkovich, Gregory, Lebedev, Vladimir
openaire +2 more sources
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
CFD Modeling of Near-Field Tornado Flow Using RANS Turbulence Models
Applied SciencesThe primary objective of this study is to model the velocity distribution in the near-field of a tornado-like flow using computational fluid dynamics (CFD) simulations conducted in ANSYS Fluent 2025 R1.
Tomasz Lamparski, Maciej Dutkiewicz
doaj +1 more source
Geomatics, Natural Hazards & Risk, 2018 Lateral berms are often constructed to protect highway bridges against debris flows in mountainous regions. Currently, different solutions for lateral berm design are debated.
Fei Qiu +7 more
doaj +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source