Results 81 to 90 of about 849,570 (300)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Addendum: "The Dynamics of M15: Observations of the Velocity Dispersion Profile and Fokker-Planck Models" (ApJ, 481, 267 [1997])

, 2002
It has recently come to our attention that there are axis scale errors in three of the figures of Dull et al. (1997, hereafter D97). D97 presented Fokker-Planck models for the collapsed-core globular cluster M15 that include a dense, centrally ...
Callanan, P. J., Charles, P. A., Cohn, H. N., Dull, J. D., Lugger, P. M., Murphy, B. W., Rutten, R. G. M., Seitzer, P. O.   +7 more
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Combined Method for Quantitative Characterisation of Fluid Flow

Applied Rheology, 2001
A method has been proposed for quantitative characterization of the flow behaviour of fluids, which is an important problem of applied rheology. Particle Image Velocimetry technique has been used for visualization and measurement of the velocity field ...
Ivanov Yatchko, Kavardjikov Vasil, Pashkuleva Dessislava   +2 more
doaj   +1 more source

Control of backward-facing step flow using burst modulation with a DBD plasma actuator

Nihon Kikai Gakkai ronbunshu, 2016
In this paper, an experimental study is performed for channel flow over a backward-facing step, with a dielectric barrier discharge (DBD) plasma actuator (PA) as a flow control device that introduces periodic disturbance to the system.
Shun OTSUKA, Masatoshi SANO, Yusuke NOGI, Shinji HONAMI   +3 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Cause of jet of vortex ring and its suppression in circular converging nozzle with entrance pipe

Nihon Kikai Gakkai ronbunshu, 2019
The control of circular jets has been studied extensively in the fluid dynamics literature. Most studies introduce an entrance pipe upstream of the nozzle outlet to straighten the flow.
Masato AKIMOTO, Motoaki KIMURA
doaj   +1 more source

Determination of the Brunt-Vaisala frequency from vertical velocity spectra [PDF]

, 1986
Recent work on the spectra of vertical velocity oscillations due to gravity waves in the troposphere, stratosphere and the mesosphere has revealed a typical feature which we call the Brunt-Vaisala cutoff.
Rottger, J.
core   +1 more source

Constraining Intermediate-Mass Black Holes in Globular Clusters

, 2012
Decades after the first predictions of intermediate-mass black holes (IMBHs) in globular clusters (GCs) there is still no unambiguous observational evidence for their existence. The most promising signatures for IMBHs are found in the cores of GCs, where
Allen, Anderson, Baraffe, Baumgardt, Baumgardt, Baumgardt, Beccari, Bettwieser, Chatterjee, Chatterjee, Dalessandro, Dinescu, Ferrarese, Frederic A. Rasio, Fregeau, Fregeau, Gill, Heggie, Joshi, Joshi, McLaughlin, Noyola, Noyola, Pasquato, Stefan Umbreit, Trenti, Umbreit, Vesperini   +27 more
core   +1 more source