Results 1 to 10 of about 4,014 (178)

Persistent Hepatitis C Viremia Following Sofosbuvir/Velpatasvir During Bendamustine‐Rituximab Therapy for Follicular Lymphoma [PDF]

open access: yesClinical Case Reports
This is a case of a 67‐year‐old female with follicular lymphoma who developed hepatitis C viremia during chemotherapy and failed treatment with a 12‐week course of sofosbuvir/velpatasvir.
Chisom J. Orakwue, Rade N. Pejic
doaj   +3 more sources

Efficacy and safety of sofosbuvir–velpatasvir and sofosbuvir–velpatasvir–voxilaprevir for hepatitis C in Korea: a Phase 3b study [PDF]

open access: yesThe Korean Journal of Internal Medicine, 2023
Background/Aims Despite the availability of direct-acting antivirals (DAAs) for chronic hepatitis C virus (HCV) infection in Korea, need remains for pangenotypic regimens that can be used in the presence of hepatic impairment, comorbidities, or prior ...
Jeong Heo   +24 more
doaj   +2 more sources

Simplified monitoring of sofosbuvir/velpatasvir in Japanese patients with chronic hepatitis C based on a retrospective analysis of a prospective multicenter cohort [PDF]

open access: yesScientific Reports
Simplified (“minimal monitoring”) pathways can expand access to direct-acting antivirals (DAAs) by reducing visit burden. In Japan, where hepatitis C virus (HCV) patients are among the oldest worldwide, whether DAA regimens can be delivered safely and ...
Goki Suda   +25 more
doaj   +2 more sources

Hepatitis C Virus (HCV) Recurrence and Death After Viral Clearance in an HCV-Viremic Donor to HCV-Negative Kidney Recipient [PDF]

open access: yesKidney Medicine
Current direct-acting antiviral (DAA) regimens have achieved nearly universal viral eradication in hepatitis C virus (HCV) nucleic acid test (NAT)-positive donor to HCV-negative recipient (HCV NAT+/–) transplantation.
Shengliang He   +8 more
doaj   +2 more sources

Real-World Effectiveness of Sofosbuvir/Velpatasvir, Glecaprevir/Pibrentasvir, and Sofosbuvir/Velpatasvir/Voxilaprevir Against Genotype 3 Hepatitis C Virus Infection: A Systematic Review and Meta-Analysis

open access: yesFrontiers in Gastroenterology
IntroductionDirect antiviral agents (DAAs) have dramatically changed the landscape of liver diseases associated with chronic hepatitis C virus (HCV) infection. However, limited data are available on the antiviral effect of sofosbuvir (SOF) + velpatasvir (
Hui-chun Xing
exaly   +3 more sources

Recent Advances in the Treatment of Chronic Hepatitis C [PDF]

open access: yesThe Korean Journal of Gastroenterology
A chronic hepatitis C virus (HCV) infection remains a major global health concern, with an estimated 50 million affected individuals. In South Korea, the prevalence of anti-HCV antibodies ranges from 0.6% to 0.8%, mainly in older adults.
Suk Bae Kim
doaj   +2 more sources

Comedications and potential drug-drug interactions with direct-acting antivirals in hepatitis C patients on hemodialysis [PDF]

open access: yesClinical and Molecular Hepatology, 2021
Background/Aims Direct‐acting antivirals (DAAs) have been approved for hepatitis C virus (HCV) treatment in patients with end-stage renal disease (ESRD) on hemodialysis.
Po-Yao Hsu   +23 more
doaj   +1 more source

SOFOSBUVIR-VELPATASVIR THERAPY IN THE TREATMENT OF CHRONIC HEPATITIS C GENOTYPE 3

open access: yesPakistan Armed Forces Medical Journal, 2021
Objective: To determine the efficacy and safety of sofosbuvir-velpatasvir combination therapy in treatment of chronic hepatitis C genotype 3. Study Design: Prospective cohort study.
Arif Qayyum Khan   +5 more
doaj   +1 more source

Effects of antiviral therapy on reducing the risk of metabolic syndrome in patients with chronic hepatitis C

open access: yesЖурнал инфектологии, 2023
Aim – to evaluate the effect of direct antiviral drugs (sofosbuvir and velpatasvir) on the formation of the metabolic syndrome in patients with chronic hepatitis C with a high risk of its development 2 years after treatment.Materials and methods.
A. F. Novikova   +3 more
doaj   +1 more source

In-Vitro and In-Vivo Evaluation of Velpatasvir- Loaded Mesoporous Silica Scaffolds. A Prospective Carrier for Drug Bioavailability Enhancement

open access: yesPharmaceutics, 2020
The limited aqueous solubility of many active pharmaceutical ingredients (APIs) is responsible for their poor performance and low drug levels in blood and at target sites. Various approaches have been adopted to tackle this issue.
Yasir Mehmood   +12 more
doaj   +1 more source

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