Results 221 to 230 of about 210,415 (275)

Bioactive peptides in cancer and inflammation: Mechanisms, model systems and clinical translation

Clinical and Translational Discovery, Volume 6, Issue 5, October 2026.
Bioactive peptides (BAPs) derived from host, marine, insect, plant and synthetic sources share cationic, amphipathic structures adopting α‐helical, β‐sheet or cyclic conformations. These features underlie anti‐cancer effects, including membrane disruption, apoptosis and cell‐cycle arrest, anti‐metastatic activity, reduced invasion and migration, and ...
Najwa Doha, Richa Gill, Sergio Crovella, Haissam Abou‐Saleh, Sahar Isa Da'as   +4 more
wiley   +1 more source

Understanding the Potential of Antibody‐Drug Conjugates Functionalized Engineered Exosomes in Hepatocellular Carcinoma Therapy: A Comprehensive Narrative Review

Health Science Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background Exosomes are naturally secreted nanovesicles with high biocompatibility, low immunogenicity, and the ability to traverse biological barriers, making them attractive theragnostic carriers. When engineered to present tumor‐specific antibodies and to deliver antibody‐drug conjugates (ADCs), they may enhance selective targeting of ...
Subham Sarkar, Avinaba Bose, Jenifer Rajak, Arup Kumar Mitra, Ajoy Kumer, Bikram Dhara   +5 more
wiley   +1 more source

Assessment of Gold‐Mediated Male Reproductive Dysfunction in Male WISTAR Rats Through Sperm Analysis and Testosterone Measurement

Journal of Applied Toxicology, Volume 46, Issue 10, Page 3403-3414, October 2026.
ABSTRACT Gold has been used for centuries in both ornamental and medicinal contexts. More recently, gold compounds, containing ions or nanoparticles, have attracted attention for their anti‐inflammatory, anticancer, and diagnostic applications. Therefore, concerns about systemic toxicity and biodistribution have prompted investigations into the ...
Samira Maghraoui, Adrian Florea, Leila Tekaya   +2 more
wiley   +1 more source

“Her Voice Is So Pleasant!”: Sexual Harassment in Chinese Law Firms

Law &Policy, Volume 48, Issue 4, October 2026.
ABSTRACT Sexual harassment is frequently observed yet rarely reported in Chinese law firms. Drawing on 103 interviews with early‐career lawyers, this article examines why women lawyers, despite possessing legal expertise that should equip them to identify and resist sexual harassment, experience harassment patterns similar to those documented in other ...
Yuyao Yi, Sida Liu
wiley   +1 more source

Peptide‐Enabled Nanoplatforms for Malaria and Leishmaniasis: From Intracellular Targeting to Translational Diagnostic Perspectives

ChemMedChem, Volume 21, Issue 18, 28 September 2026.
Peptide‐enabled nanoplatforms offer multifunctional strategies for the treatment and diagnosis of malaria and leishmaniasis. Liposomal, polymeric, and metallic nanocarriers, together with cell‐penetrating peptides and parasite‐derived mimotopes, can improve targeted drug delivery, stability, bioavailability, and intracellular localization.
Christian S. Carnero Canales, Ana Clara Lunardi Yagi, Túlio Custódio Reis, Jessica Ingrid Cazorla, Jade Rojas Villar, Marcia A. Graminha, Roxana Yesenia Pastrana Alta, Fernando Rogério Pavan   +7 more
wiley   +1 more source

Intraspecific venom variation in the medically important puff adder ( Bitis arietans ): comparative venom gland transcriptomics, in vitro venom activity and immunological recognition by antivenom

Dawson CA, Bartlett KE, Wilkinson MC, Ainsworth S, Albulescu L, Kazandijan T, Hall SR, Westhorpe A, Clare R, Wagstaff S, Modahl CM, Harrison RA, Casewell NR.   +12 more
europepmc   +1 more source

Venom gland and reservoir morphology in cynipoid wasps

Arthropod Structure & Development, 2006
The venom apparatus morphology was examined in 25 species of Cynipoidea, representing 11 parasitoid taxa; 12 gall inducers and two inquilines. Typically the venom apparatus consists of an oval or bilobed reservoir connected to the ovipositor apparatus by a very short venom duct at the anterior end and to a single elongate unbranched venom gland at or ...
Vårdal, Hege,
openaire   +3 more sources

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Venom gland transcriptomics for identifying, cataloging, and characterizing venom proteins in snakes

Toxicon, 2015
Snake venoms are cocktails of protein toxins that play important roles in capture and digestion of prey. Significant qualitative and quantitative variation in snake venom composition has been observed among and within species. Understanding these variations in protein components is instrumental in interpreting clinical symptoms during human ...
Ryan J R McCleary, Robin Doley, Manjunatha Kini   +2 more
exaly   +3 more sources

Venom glands in scatophagid fish

Toxicon, 1970
Venom glands have been demonstrated in scatophagid fishes for the first time. Six specimens of Scatophagus argus, from 62 mm to 296 mm in standard length, possessed a pair of venom glands accommodated in paired antero-lateral grooves in each fin spine. The venom glands of the larger specimens were shorter than those of the smaller fishes. In Selenotoca
Cameron A.M., Endean R.
openaire   +5 more sources

Unmasking venom gland transcriptomes in reptile venoms

Analytical Biochemistry, 2002
While structural studies of reptile venom toxins can be achieved using lyophilized venom samples, until now the cloning of precursor cDNAs required sacrifice of the specimen for dissection of the venom glands. Here we describe a simple and rapid technique that unmasks venom protein mRNAs present in lyophilized venom samples. To illustrate the technique
Chen, Tianbao, Bjourson, A.J., Orr, D.F., Kwok, H.F., Ivanyi, C., Rao, P.F., Shaw, Christopher   +6 more
openaire   +3 more sources