Results 101 to 110 of about 86,490 (305)

Endothelial inflammation and thrombotic risk: From the leg to the pelvis and back

Turkish Journal of Vascular Surgery
Pathological shear and stretch stress acting on the endothelium lining following venous reflux has been associated with an increased risk not only of thrombosis, but also of pan-endothelial inflammation.
Sergio Gianesini, Suat Doganci
doaj  

Oxygen Supply of Islets of Langerhans by Photosynthetically Active Microalgae in Bioprinted Co‐Cultures Maintains Their Function in a Hypoxic Environment

Advanced Healthcare Materials, EarlyView.
This study developed a bioprinted co‐culture system embedding rat pancreatic islets and Scenedesmus sp. microalgae spatially defined in close vicinity. Red light was found optimal to ensure microalgal photosynthesis while maintaining islet viability and functionality. A tailored co‐culture medium supported both cell types.
Finn Dani, Sarah Duin, Ashwini Rahul Akkineni, Susann Lehmann, Barbara Ludwig, Michael Kühl, Michael Gelinsky, Anja Lode   +7 more
wiley   +1 more source

Renal Lymphatics: Anatomy, Physiology, and Clinical Implications

Frontiers in Physiology, 2019
Renal lymphatics are abundant in the cortex of the normal kidney but have been largely neglected in discussions around renal diseases. They originate in the substance of the renal lobule as blind-ended initial capillaries, and can either follow the main ...
Peter Spencer Russell, Peter Spencer Russell, Jiwon Hong, Jiwon Hong, John Albert Windsor, Maxim Itkin, Anthony Ronald John Phillips, Anthony Ronald John Phillips   +7 more
doaj   +1 more source

Opinion: Gavage Administration of MXene as a Route‐Specific Alternative to Intravenous Injection into the Bloodstream of Laboratory Animals for Reducing Systemic Nanotoxicity Risks in Immunosuppression and Post‐Transplantation Models with Bile Acid Modification

Advanced Healthcare Materials, EarlyView.
Recent studies reported immunosuppressive properties of specific MXene nanomaterials. Their intravenous injection into the bloodstream of laboratory animals has been a common delivery method to suppress systemic inflammation and prevent transplant rejection.
Alireza Rafieerad, M. Akif Rahman, Ahmad Amiri   +2 more
wiley   +1 more source

Escin: a review of its anti-edematous, anti-inflammatory, and venotonic properties

Drug Design, Development and Therapy, 2019
Luca Gallelli1,2 1Department of Health Science, School of Medicine, University of Catanzaro, Catanzaro, Italy; 2Operative Unit of Clinical Pharmacology and Pharmacovigilance, Azienda Ospedaliera Mater Domini, Catanzaro, ItalyCorrespondence: Luca ...
Gallelli L
doaj  

Permeability and distribution of nerve growth factor in the brain of neonatal rats by periphery venous injection in hypoxic-ischemic state

SpringerPlus, 2016
To investigate the permeability of β-NGF through blood-brain-barrier (BBB) in neonatal and adult rats, and the spatial distribution of β-NGF in different brain regions in hypoxic-ischemic (HI) and normal neonatal rats.To investigate the overall permeability of β-NGF through BBB, β-NGF labeled with I125 was injected into adult rats, neonatal rats and HI
Zhou, Wenli, Zhang, Jiantao, Wang, Guangming, Ling, Limian, Yan, Chaoying   +4 more
openaire   +2 more sources

Ultrasound‐Responsive Dual‐Prodrug Nanoassembly for “Fenestrae‐Restoration Strategy” in Liver Fibrosis Therapy

Advanced Materials, EarlyView.
ABSTRACT Liver fibrosis is a serious yet reversible intermediate stage in the progression of liver disease, which can ultimately advance to cirrhosis and hepatocellular carcinoma. Targeted and selective inhibition of activated hepatic stellate cells (aHSCs) has emerged as a promising therapeutic strategy for the treatment of liver fibrosis.
Shutong Liu, Mengyao Zhang, Zitong Qiu, Xinyi Liu, Yunsheng Dou, Sona Krizkova, Zheyi Li, Zbynek Heger, Nan Li   +8 more
wiley   +1 more source

Cell–cell signaling in blood vessel development and function

EMBO Molecular Medicine, 2018
The blood vasculature is an organ pervading all other organs (almost). During vascular development, cell–cell signaling by extracellular ligands and cell surface receptors ensure that new vessels sprout into non‐vascularized regions and simultaneously ...
Christer Betsholtz
doaj   +1 more source

Deployable 3D‐Printed Vascular Stent with Surface‐Catalysed Endogenous Nitric Oxide Generation

Advanced Materials, EarlyView.
A deployable 3D‐printed vascular stent was fabricated with surface‐catalyzed endogenous nitric oxide generation, representing a promising new direction for stent development. The stent can be remotely controlled by magnetic force in its compressed state and fully deployed at the target site using an untethered heat source, potentially eliminating the ...
Kun Zhou, Zifei Han, Kang Lin, Di Wu, Siti Nur Asyura Adzlan, Qingqing Fan, Christina Cortez‐Jugo, Rona Chandrawati, Cyrille Boyer   +8 more
wiley   +1 more source

Downstream Microvascular Thrombosis in Cortical Venules Is an Early Response to Proximal Cerebral Arterial Occlusion

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
BackgroundPrevious experimental studies have shown that downstream microvascular thromboinflammation is involved in brain damage from acute ischemic stroke.
Jean‐Philippe Desilles, Varouna Syvannarath, Lucas Di Meglio, Célina Ducroux, William Boisseau, Liliane Louedec, Martine Jandrot‐Perrus, Jean‐Baptiste Michel, Mikael Mazighi, Benoît Ho‐Tin‐Noé   +9 more
doaj   +1 more source