Results 91 to 100 of about 491,136 (305)
SerpinA3 acts as an endogenous TGF‐β receptor antagonist that binds to the extracellular domain of TGFR‐1, thereby preventing TGFR‐1–TGFR‐2 complex formation. This receptor‐level blockade suppresses TGF‐β/Smad2/3 signaling, attenuates cardiac fibroblast activation, and extracellular matrix deposition, and ultimately alleviates pressure overload–induced
Hui Wang +9 more
wiley +1 more source
Venous thrombosis remains a significant cause of maternal mortality and long-term morbidity, both in the developing and developed world. This review details the pathophysiology of venous thromboembolism in pregnancy and outlines the appropriate risk ...
Clark, Peter
core +1 more source
Clinical characteristics of splanchnic venous thrombosis (SpVT).
Clinical characteristics of splanchnic venous thrombosis (SpVT).
Soo-Mee Bang (14433) +12 more
core +1 more source
RBMS1, an RNA‐binding protein, restores vascular endothelial homeostasis by enhancing ATG3‐mediated autophagy, thereby attenuating thrombus formation and suggesting a potential avenue for further therapeutic exploration in DVT. ABSTRACT Deep vein thrombosis (DVT) is a prevalent vascular disorder characterized by aberrant coagulation within the deep ...
Chu Chu +13 more
wiley +1 more source
Comparative frequency of Coagulation Factor II and Coagulation Factor V Alleles among new-born and senior citizens [PDF]
Resistance to activated protein C is one of the most common inherited disorders associated with hereditary thrombophilia. A missense mutation in the gene coding for coagulation factor V (CF V Leiden) and which renders this procoagulant factor resistant ...
Bezzina Wettinger, Stephanie +4 more
core
Discrepant ratios of arterial versus venous thrombosis in hemophilia A as compared with hemophilia B
The occurrence of thrombosis in patients with congenital bleeding disorders represents an exceptional event. Hemophilia A and hemophilia B patients have been showed to present both arterial and venous thrombosis (85 cases of arterial thrombosis and 34 ...
Irene Bertozzi +9 more
core +1 more source
THSD7A Exacerbates Atherosclerosis via Activation of Signaling Axis αvβ3/CEBPD/IL1A
THSD7A exerts pro‐inflammatory effects and exacerbates atherosclerosis. Mechanistically, THSD7A regulates endothelial cell inflammation and atherosclerosis by activating the αvβ3/CEBPD/IL1A signaling axis. THSD7A is not only a genetic marker but also a potential therapeutic target for coronary artery disease (CAD).
Jiankun Liu +15 more
wiley +1 more source
ULTRASOUND DIAGNOSIS OF THROMBOSIS IN CANCER PATIENTS
Purpose. To identify the relationship between ultrasonographic signs of progression of venous thrombosis and procoagulant activity of malignant tumors.Material and methods.
F. S. Akhmetzianov, I. A. Kamalov
doaj +1 more source
The diagnostic work-up of upper and of lower extremity deep vein thrombosis starts with the assessment of the pre-test probability by using a validated clinical decision rule, followed by imaging if deep vein thrombosis cannot reliably be rule out.
Charlotte E. A. Dronkers +2 more
core +1 more source
A thrombin‐functionalized copper‐polydopamine nanofiber sponge integrates rapid hemostasis, mild photothermal antibacterial therapy, stimulus‐responsive Cu2+ release, chemodynamic oxidative stress, and macrophage immunomodulation. This multifunctional dressing suppresses infection, regulates inflammation, promotes angiogenesis and re‐epithelialization,
Ziwei Zhang +11 more
wiley +1 more source

