Results 101 to 110 of about 290,212 (305)

Tumor‐Induced Splenic Remodeling: Mechanisms of Systemic Immunosuppression and Emerging Therapeutic Opportunities

Advanced Science, EarlyView.
ABSTRACT Despite the transformative impact of cancer immunotherapies such as immune checkpoint blockade, durable clinical responses remain limited. Increasing evidence indicates that antitumor immunity is governed not only by the tumor microenvironment, but also by systemic immune regulation mediated by peripheral immune organs. Among these, the spleen
Yuehua Liu, Xiaoqian Nie, Xiaofei Gao
wiley   +1 more source

Risk factors for peripherally inserted central catheter line–related deep venous thrombosis in critically ill intensive care unit patients

SAGE Open Medicine, 2020
Introduction: Central venous access using peripherally inserted central catheters is frequently used for patients receiving intravenous medications in the hospital or outpatients.
M Bhargava, S Broccard, Y Bai, B Wu, EH Dincer, A Broccard   +5 more
doaj   +1 more source

Influence of Long-term Cytotoxic Chemotherapy on the Condition of Peripheral Venous Channel [PDF]

, 2017
The necessity of long-term venous access in cancer patients appears at frequent and long-term courses of cytotoxic therapy. Peripheral veins of forearms are most often used for these aims. The conditions of peripheral venous channel in 32 cancer patients,
Tkachuk, T. (Tetiana)
core   +2 more sources

A Biomimetic Nanoparticle System Intercepts and Degrades Thrombospondin‐1 to Restore Vascular Homeostasis After Ischemic Injury

Advanced Science, EarlyView.
TAX2‐NPs capture extracellular TSP‐1 in the injured liver and promote its macrophage‐mediated autophagic degradation. This process blocks TSP‐1/CD47 signaling, restores VEGFR2‐AKT activity, preserves endothelial function, and mitigates hepatic ischemia‐reperfusion injury.
Haorui Wang, Xiandi Meng, Yanbao Xin, Kuirong Mao, Huizhu Tan, Changkai Ma, Xiuxiu Cong, Mengfei Zhao, Meiling Yu, Si Chen, Yue Hou, Yong‐Guang Yang, Tianmeng Sun   +12 more
wiley   +1 more source

Metabolic landscape in venous thrombosis: insights into molecular biology and therapeutic implications

Annals of Medicine
The findings of the last decade suggest a complex link between inflammatory cells, coagulation, and the activation of platelets and their synergistic interaction to promote venous thrombosis.
Zheng Cao, Xuejun Jiang, Yiyu He, Xiaoxin Zheng   +3 more
doaj   +1 more source

Anticoagulants for acute ischaemic stroke [PDF]

, 2015
Peer reviewedPublisher ...
Counsell, Carl, Kane, Edward J, Sandercock, Peter A G   +2 more
core   +1 more source

Which Method Best Predicts Postoperative Complications: Deep Learning, Machine Learning, or Conventional Logistic Regression?

Annals of Gastroenterological Surgery, EarlyView.
Deep learning has shown promise in predicting postoperative complications, particularly when using image or time‐series data. However, on tabular clinical data such as the NCD, it often underperforms compared to conventional machine learning. Integrating multimodal data may enhance predictive accuracy and interpretability in surgical care.
Ryosuke Fukuyo, Masanori Tokunaga, Hiroyuki Yamamoto, Hideki Ueno, Yusuke Kinugasa   +4 more
wiley   +1 more source

Impact of sepsis on risk of postoperative arterial and venous thromboses: large prospective cohort study [PDF]

, 2014
Objectives: To evaluate the impact of preoperative sepsis on risk of postoperative arterial and venous thromboses. Design: Prospective cohort study using the National Surgical Quality Improvement Program database of the American College of Surgeons (ACS ...
Bates, David W, Donzé, Jacques D, Finlayson, Samuel R G, Ridker, Paul M   +3 more
core   +2 more sources

Elevated Risk of Complications in Patients Receiving Dual Antithrombotic Therapy Undergoing Hepatectomy: A Single‐Center Audit of 749 Cases

Annals of Gastroenterological Surgery, EarlyView.
This single‐center retrospective study evaluated perioperative outcomes after hepatectomy in 749 patients, including 140 receiving ATT, using propensity score matching to compare ATT and non‐ATT cohorts. Under standardized perioperative management, ATT did not increase major bleeding, transfusion, or severe morbidity overall; however, within the ATT ...
Haruki Mori, Hiromitsu Maehira, Nobuhito Nitta, Takeru Maekawa, Toru Miyake, Sachiko Kaida, Masatsugu Kojima, Katsushi Takebayashi, Takeshi Sonoda, Masaji Tani   +9 more
wiley   +1 more source

CEREBRAL VENOUS THROMBOSIS IN OBSTETRICS AND GYNECOLOGY

Акушерство, гинекология и репродукция, 2016
Cerebral venous thrombosis is a rare, life-threatening condition, which has now become more frequently diagnosed by advances in imaging techniques. The most common risk factors for cerebral venous thrombosis include pregnancy, postpartum period, use of ...
A. D. Makatsariya, S. V. Akinshina, V. O. Bitsadze   +2 more
doaj