Results 121 to 130 of about 290,212 (305)

The Impact of Anticoagulation in Patients With Isolated Cancer‐Associated Splanchnic Vein Thrombosis: A Dual‐Center Cohort Study

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Data to guide management of isolated bland cancer‐associated splanchnic vein thrombosis (CA‐SpVT) are limited. We aimed to assess the role of anticoagulation (AC) and bleeding and thrombosis in patients with CA‐SpVT. We conducted a dual‐center retrospective cohort study of adults with incident, isolated, bland CA‐SpVT from 2011 to 2020.
Abhilasha Borad   +9 more
wiley   +1 more source

Concentration and the value of D-dimer in the diagnosis of deep vein thrombosis

open access: yesRevista Cubana de Medicina Militar, 2023
  Introduction: Quantification of D-dimer levels is a valuable test in orienting the diagnosis of deep vein thrombosis. Objectives: Determine D-dimer concentration and diagnostic value of D-dimer in patients with deep venous thrombosis.
Van Nguyen-Thanh Phan   +5 more
doaj  

Safety and Effectiveness of Sutimlimab in Cold Agglutinin Disease: A Real‐World International Experience

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Sutimlimab is a monoclonal antibody against complement fraction C1s approved for the treatment of hemolytic anemia due to cold agglutinin disease (CAD). Here, we analyzed and report the largest international CAD cohort of sutimlimab‐treated patients ever reported to highlight its safety and effectiveness in the real‐world setting. We accrued a
Bruno Fattizzo   +38 more
wiley   +1 more source

Dicumarol [PDF]

open access: yes, 1945
Thesis (M.D.)--Boston ...
Steel, Robert MacDonald
core  

Pathogenic PF4/Polyanion ELISA‐Negative Antibodies in HIT

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Background Platelet factor 4‐polyanion enzyme‐linked immunosorbent assays (ELISAs) are considered highly sensitive for diagnosing heparin‐induced thrombocytopenia (HIT), such that current practice guidelines recommend use of ELISA‐negative results to exclude HIT.
Adam J. Kanack   +25 more
wiley   +1 more source

A novel role for protein disulfide isomerase ERp18 in venous thrombosis

open access: yesThrombosis Journal
Background Previous studies using genetically modified mouse models and inhibitors have shown that protein disulfide isomerase (PDI) family plays a significant role in arterial thrombosis. However, their role in venous thrombosis remains unknown. In this
Chao He   +6 more
doaj   +1 more source

Cerebral venous thrombosis and depression: a scoping review

open access: yesMedičnì Perspektivi
 Cerebral venous thrombosis is a rare condition involving thrombus formation in the venous sinuses of the brain, leading to impaired venous drainage, increased intracranial pressure, and brain damage.
Feras M. Almarshad, Dushad Ram
doaj   +1 more source

Dupilumab Beyond the Airway: Decreased Morbidity in a Real‐World Analysis

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Post hoc analyses of clinical trials have characterized dupilumab's adverse effects, yet the real‐world impact in chronic rhinosinusitis with nasal polyps (CRSwNP) and asthma is not well described. This study aims to characterize the risks of lymphoma, cardiovascular events, eosinophilia, joint pain, inflammatory arthritis, and ...
Emma J. Anisman   +9 more
wiley   +1 more source

Genetic predisposition to porto‐sinusoidal vascular disorder: A functional genomic‐based, multigenerational family study

open access: yesHepatology, EarlyView., 2022
A deleterious variant of FCHSD1 results in mTOR pathway overactivation and may cause porto‐sinusoidal vascular disorder (PSVD). The pedigree of the family demonstrated an autosomal dominant disease with variable expressivity. Whole‐genome sequencing and Sanger sequencing both validated the existence of the FCHSD1 variant and the heterozygosity of c ...
Jingxuan Shan   +19 more
wiley   +1 more source

Venous and arterial thrombosis in patients receiving immune checkpoint inhibitors.

open access: yesPLoS ONE
BackgroundImmune checkpoint inhibitors (ICPi) have been associated with a prothrombotic and pro-atherogenic tendency which could lead to an increased risk of thrombosis.
Anouk van Lent   +7 more
doaj   +1 more source

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